Abstract 3D-printed composite scaffolds have emerged as an alternative to deal with existing
limitations when facing bone reconstruction. The aim of the study was to systematically …

Over the decades, researchers have strived to synthesize and modify nature-inspired
biomaterials, with the primary aim to address the challenges of designing functional …

The advancement of tissue engineering for regenerating injured tissues and organs has
progressed significantly in recent years. Various techniques have been used to modify the …

The management and definitive treatment of segmental bone defects in the setting of acute
trauma, fracture non-union, revision joint arthroplasty, and tumor surgery are challenging …

Self-healing and autologous bone graft of calvaraial defects can be challenging. Therefore,
the fabrication of scaffolds for its rapid and effective repair is a promising field of research …

Poly (lactic acid)(PLA) is widely used in the field of medicine due to its biocompatibility,
versatility, and cost-effectiveness. Three-dimensional (3D) printing or the systematic …

Despite the recent advances in the development of bone graft substitutes, treatment of
critical size bone defects continues to be a significant challenge, especially in the elderly …

Reconstruction of critical-size bone defects (CSDs) in the craniomaxillofacial (CMF) region
remains challenging. Scaffold-based bone-engineered constructs have been proposed as …

Polydopamine (PDA) films, when combined with model nanometric semiconductor
substrates like titanium dioxide (TiO 2) and zinc oxide (ZnO), enhance photocatalytic …

Gene therapy has emerged as a highly promising strategy for the clinical treatment of large
segmental bone defects and non-union fractures, which is a common clinical need …