Abdominal sepsis: an update

MG Mureșan, IA Balmoș, I Badea… - The Journal of Critical …, 2018 - sciendo.com
Despite the significant development and advancement in antibiotic therapy, life-threatening
complication of infective diseases cause hundreds of thousands of deaths world. This paper …

Abdominal compartment syndrome as a multidisciplinary challenge. A literature review

GA Popescu, T Bara, P Rad - The Journal of Critical Care Medicine, 2018 - sciendo.com
Abstract Abdominal Compartment Syndrome (ACS), despite recent advances in medical and
surgical care, is a significant cause of mortality. The purpose of this review is to present the …

Effects of anti-IL-17 on inflammation, remodeling, and oxidative stress in an experimental model of asthma exacerbated by LPS

LN Camargo, RF Righetti, LRCRB Aristóteles… - Frontiers in …, 2018 - frontiersin.org
Inflammation plays a central role in the development of asthma, which is considered an
allergic disease with a classic Th2 inflammatory profile. However, cytokine IL-17 has been …

Calcium-sensitive receptors alters intestinal microbiota metabolites especially SCFAs and ameliorates intestinal barrier damage in neonatal rat endotoxemia

Y Sun, J Song, X Lan, F Ma, M Jiang… - Infection and Drug …, 2023 - Taylor & Francis
Purpose The calcium-sensing receptor (CaSR) acts as a major modulator of tissue
responses related to calcium homeostasis and expresses highly in the mammalian intestine …

Progression of Acute Lung Injury in Intratracheal LPS Rat Model: Efficacy of Fluticasone, Dexamethasone, and Pirfenidone

AH Kadam, JE Schnitzer - Pharmacology, 2024 - karger.com
Introduction: We investigated the potential of LPS (10–300 µg/rat) administered
intratracheally (it) to induce reproducible features of acute lung injury (ALI) and compared …

Both UFH and NAH alleviate shedding of endothelial glycocalyx and coagulopathy in LPS‑induced sepsis

X Huang, S Han, X Liu, T Wang… - Experimental and …, 2020 - spandidos-publications.com
Sepsis commonly progresses to disseminated intravascular coagulation and induces the
activation of heparanase (HPA) and the shedding of endothelial glycocalyx constituents …

Lipopolysaccharides induce a RAGE-mediated sensitization of sensory neurons and fluid hypersecretion in the upper airways

M Nair, S Jagadeeshan, G Katselis, X Luan… - Scientific reports, 2021 - nature.com
Thoracic dorsal root ganglia (tDRG) contribute to fluid secretion in the upper airways.
Inflammation potentiates DRG responses, but the mechanisms remain under investigation …

Losartan, a selective antagonist of AT1 receptor, attenuates seawater inhalation induced lung injury via modulating JAK2/STATs and apoptosis in rat

C Li, L Bo, P Li, X Lu, W Li, L Pan, Y Sun, D Mu… - Pulmonary …, 2017 - Elsevier
Losartan is a selective antagonist of AngⅠ type (AT1) receptor of Angiotensin Ⅱ (Ang Ⅱ),
which is widely used as a clinical medicine for the hypertension. Recent studies have shown …

Perindopril ameliorates lipopolysaccharide-induced brain injury through modulation of angiotensin-II/angiotensin-1-7 and related signaling pathways

EAM El-Shoura, BAS Messiha, SMZ Sharkawi… - European Journal of …, 2018 - Elsevier
Localized tissue renin-angiotensin system (RAS) is an interesting pathway of organ
damage. Here, the effect of the brain-penetrating angiotensin converting enzyme (ACE) …

Selective activation and proliferation of a quiescent stem cell population in the neuroepithelial body microenvironment

L Verckist, I Pintelon, JP Timmermans, I Brouns… - Respiratory …, 2018 - Springer
Background The microenvironment (ME) of neuroepithelial bodies (NEBs) harbors densely
innervated groups of pulmonary neuroendocrine cells that are covered by Clara-like cells …