Phenolic compounds are the most abundant secondary metabolites in plants, showing a
wide range of distinct biological activities, have received more and more attention in recent …

Parkinson's disease is a common neurodegenerative disorder in which gastrointestinal
symptoms may appear prior to motor symptoms. The gut microbiota of patients with …

Oxidative stress has been implicated in the pathogenesis of Alzheimer's disease (AD).
Mitochondrial dysfunction is linked to oxidative stress and reactive oxygen species (ROS) in …

Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …

Background: In developed countries, the extension of human life is increasingly
accompanied by a progressive increase in neurodegenerative diseases, most of which do …

Neurodegenerative diseases (NDs) cause progressive loss of neurons in nervous system.
NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs …

Parkinson's disease (PD) is the second most prevalent late-age onset neurodegenerative
disorder, affecting 1% of the population after the age of about 60 years old and 4% of those …

An intermediate of tricarboxylic acid cycle alpha-ketoglutarate (AKG) is involved in
pleiotropic metabolic and regulatory pathways in the cell, including energy production …

Worldwide, over 2.2 million people suffer from multiple sclerosis (MS), a multifactorial
demyelinating disease of the central nervous system. MS is characterized by a wide range of …

Olive tree-derived products have been associated with numerous benefits for health. The
aim of the present study was to characterize an olive leaf extract enriched in oleuropein …