Insights into role of microRNA in Alzheimer's disease: from contemporary research to bedside perspective

M Bandakinda, A Mishra - International Journal of Biological …, 2023 - Elsevier
One of the most prevalent neurodegenerative disorders is Alzheimer's disease (AD). Despite
the pervasiveness of AD being considerable, the rates of both diagnosis and therapy are …

Potential implications of miRNAs in the pathogenesis, diagnosis, and therapeutics of Alzheimer's disease

L Wang, X Shui, Y Diao, D Chen, Y Zhou… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a complex multifactorial disorder that poses a substantial
burden on patients, caregivers, and society. Considering the increased aging population …

Cerebrospinal fluid microRNAs as potential biomarkers in Alzheimer's disease

A Noor Eddin, K Hamsho, G Adi… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the leading form of dementia worldwide, but its early detection
and diagnosis remain a challenge. MicroRNAs (miRNAs) are a group of small endogenous …

[HTML][HTML] Decreased miR-451a in cerebrospinal fluid, a marker for both cognitive impairment and depressive symptoms in Alzheimer's disease

H Feng, P Hu, Y Chen, H Sun, J Cai, X He, Q Cao… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: Alzheimer's disease (AD) patients are often accompanied by depressive
symptoms, but its underlying mechanism remains unclear. The present study aimed to …

New approach for early and specific Alzheimer disease diagnosis from different plasma biomarkers

A Forte, S Lara, C Peña-Bautista, M Baquero… - Clinica Chimica …, 2024 - Elsevier
Abstract Background Alzheimer Disease (AD) is a complex pathology, in which several
biochemical pathways could be involved. Therefore, the development of clinical studies …

Non-invasive biomarkers for early detection of Alzheimer's disease: a new-age perspective

NMA Chimthanawala, A Haria, S Sathaye - Molecular Neurobiology, 2024 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that primarily affects
the elderly population. It gradually leads to memory loss, loss of thinking ability, and an …

Profiling Small RNA From Brain Extracellular Vesicles in Individuals With Depression

P Ibrahim, R Denniston, H Mitsuhashi… - International Journal …, 2024 - academic.oup.com
Background Major depressive disorder (MDD) is a leading cause of disability with significant
mortality risk. Despite progress in our understanding of the etiology of MDD, the underlying …

[HTML][HTML] Epigenetics of Ageing and Psychiatric Disorders

CI Colită, I Udristoiu, DL Ancuta… - Journal of Integrative …, 2024 - imrpress.com
Both classic epigenetic modifications and microRNAs can impact a range of bodily
processes, from metabolism to brain function, and may contribute to the development of …

[HTML][HTML] The role of exosome-shuttled miRNAs in heavy metal-induced peripheral tissues and neuroinflammation in Alzheimer's disease

Q Dong, H Fu, H Jiang - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Heavy metal-induced neuroinflammation is a significant pathophysiologic mechanism in
Alzheimer's disease (AD). Microglia-mediated neuroinflammation plays a crucial role in the …

Exploring the Regulatory Landscape of Dementia: Insights from Non-Coding RNAs

J Kim, WR Kim, EG Park, DH Lee, YJ Lee… - International Journal of …, 2024 - mdpi.com
Dementia, a multifaceted neurological syndrome characterized by cognitive decline, poses
significant challenges to daily functioning. The main causes of dementia, including …