I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

Importance The National Action Plan for Combating Antibiotic-Resistant Bacteria set a goal
of reducing inappropriate outpatient antibiotic use by 50% by 2020, but the extent of …

Summary The Core Elements of Outpatient Antibiotic Stewardship provides a framework for
antibiotic stewardship for outpatient clinicians and facilities that routinely provide antibiotic …

Objective This update of a 2007 guideline from the American Academy of Otolaryngology—
Head and Neck Surgery Foundation provides evidence-based recommendations to manage …

Importance The large overlap between symptoms of acute sinusitis and viral upper
respiratory tract infection suggests that certain subgroups of children being diagnosed with …

METHODS: In a retrospective cohort study using 2015–2016 claims data from a large
national commercial health plan, we identified ARI visits by children (0–17 years old) …

Importance Acute respiratory tract infections account for the majority of antibiotic exposure in
children, and broad-spectrum antibiotic prescribing for acute respiratory tract infections is …

β-Lactam drugs (penicillins, amoxicillin, and cephalosporins) account for 42.6% of all severe
drug-induced anaphylaxis. In this review, we focus on clinically significant immunologic …

Importance Acute respiratory infections (ARIs) are the syndrome for which antibiotics are
most commonly prescribed; viruses for which antibiotics are ineffective cause most ARIs …