Impact of wildfires on cardiovascular health

VA Williams, LR Perreault, CT Yazbeck… - Circulation …, 2024 - Am Heart Assoc
Wildfire smoke (WFS) is a mixture of respirable particulate matter, environmental gases, and
other hazardous pollutants that originate from the unplanned burning of arid vegetation …

E-cigarette vapor exposure in utero causes long-term pulmonary effects in offspring

DM Aslaner, O Alghothani… - … of Physiology-Lung …, 2022 - journals.physiology.org
The in utero environment is sensitive to toxicant exposure, altering the health and growth of
the fetus, and thus sensitive to contaminant exposure. Though recent clinical data suggest …

[HTML][HTML] The utility of hybrid in silico models of airflow and aerosol dosimetry in the lung

JM Oakes - Journal of Biomechanics, 2024 - Elsevier
The development and application of multi-scale models of the lung has significantly
increased in recent years. These hybrid models merge realistic representations of the larger …

Mapping the unicellular transcriptome of the ascending thoracic aorta to changes in mechanosensing and mechanoadaptation during aging

CF Rivera, YM Farra, M Silvestro, S Medvedovsky… - Aging …, 2024 - Wiley Online Library
Aortic stiffening is an inevitable manifestation of chronological aging, yet the mechano‐
molecular programs that orchestrate region‐and layer‐specific adaptations along the length …

Prolonged smoldering Douglas fir smoke inhalation augments respiratory resistances, stiffens the aorta, and curbs ejection fraction in hypercholesterolemic mice

MJ Eden, J Matz, P Garg, M Perera-Gonzalez… - Science of The Total …, 2023 - Elsevier
While mounting evidence suggests that wildland fire smoke (WFS) inhalation may increase
the burden of cardiopulmonary disease, the occupational risk of repeated exposure during …

E-cigarette aerosol exposure effect on bone biomechanical properties in murine models

M Morgan, YM Farra, A Vergara-Anglim, C Bellini… - Journal of …, 2024 - Elsevier
Numerous studies have shown the detrimental health effects of tobacco smoking on bone
volume and strength in human and animal models. Little is known regarding the impacts of e …

Respiratory mechanics following chronic cigarette smoke exposure in the Apoe mouse model

J Matz, YM Farra, HM Cotto, C Bellini… - … and Modeling in …, 2023 - Springer
Even though cigarette smoking (CS) has been on the decline over the past 50 years, it is still
the leading cause of preventable premature death in the United States. Preclinical models …

Map2k6 is a potent genetic modifier of arterial rupture in vascular Ehlers-Danlos syndrome mice

CJ Bowen, R Sorber, JFC Giadrosic, JJ Doyle, G Rykiel… - JCI insight, 2025 - insight.jci.org
Aortic dissection or rupture is a major cause of mortality in vascular Ehlers-Danlos
Syndrome (vEDS), a connective tissue disorder caused by heterozygous mutations in the …

Differential Toxicity of Electronic Cigarette Aerosols Generated from Different Generations of Devices In Vitro and In Vivo

T Ma, H Chen, YP Liao, J Li, X Wang, L Li… - Environment & …, 2023 - ACS Publications
Electronic cigarettes (e-cigs) have become increasingly popular, especially among youth,
raising concerns about their potential health risks. JUUL and Tank devices are two common …

Development of Murine Models of E-Cig Aerosol and Wildland Fire Smoke Inhalation: Leveraging Experimental-Computational Methods to Investigate …

MJ Eden - 2023 - search.proquest.com
The toxicity of inhaled pollutants depends on the size and chemical composition of their
particulates, with fine and ultrafine particles considered more toxic because of their ability to …