Genetic studies have typically inferred the effects of human impact by documenting patterns
of genetic differentiation and levels of genetic diversity among potentially isolated …

Proteins encoded by the classical major histocompatibility complex (MHC) genes incite the
vertebrate adaptive immune response by presenting peptide antigens on the cell surface …

To maintain sexual reproduction, recombination of good genes through selective mate
choice must achieve a twofold genetic benefit in each generation.“Fragrant” immune genes …

T cell discrimination of self and non-self is the foundation of the adaptive immune response,
and is orchestrated by the interaction between T cell receptors (TCRs) and their cognate …

Proteins of the major histocompatibility complex (MHC) play a central role in the
presentation of antigens to the adaptive immune system. The MHC also influences the odour …

The major histocompatibility complex (MHC) genes code for the proteins responsible for
pathogen recognition. The MHC class II DRB gene is multiplicated in the bank vole, Myodes …

An adaptive immune response is usually initiated only if a major histocompatibility complex
(MHC) molecule presents pathogen-derived peptides to T-cells. Every MHC molecule can …

Individual diversity at the major histocompatibility complex (MHC) is predicted to be optimal
at intermediate rather than at maximal levels. We showed previously in sticklebacks that an …

Major histocompatibility complex (MHC) genes encode proteins that initiate adaptive
immune responses through the presentation of foreign antigens to T cells. The high …

The peripheral T cell repertoire is sculpted from prototypic T cells in the thymus bearing
randomly generated T cell receptors (TCR) and by a series of developmental and selection …