Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

Precise gene expression ensures proper stem and progenitor cell differentiation, lineage
commitment and organogenesis during mammalian development. ATP-dependent …

Low-complexity protein domains promote the formation of various biomolecular
condensates. However, in many cases, the precise sequence features governing …

Transcription factors (TFs) interact with several other proteins in the process of
transcriptional regulation. Here, we identify 6703 and 1536 protein–protein interactions for …

The Snf2 family of helicase-related proteins includes the catalytic subunits of ATP-
dependent chromatin remodelling complexes found in all eukaryotes. These act to regulate …

The nucleosomal landscape of chromatin depends on the concerted action of chromatin
remodelers. The INO80 remodeler specifically places nucleosomes at the boundary of gene …

Chromatin-modifying factors have essential roles in DNA processing pathways that dictate
cellular functions. The ability of chromatin modifiers, including the INO80 and SWR1 …

The APC tumor suppressor controls the stability and nuclear export of β-catenin (β-cat), a
transcriptional coactivator of LEF-1/TCF HMG proteins in the Wnt/Wg signaling pathway. We …

Adenosine triphosphate‐dependent chromatin remodeling complexes are important for the
regulation of transcription, DNA replication, and genome stability in eukaryotes. Although …

Human MOF (MYST1), a member of the MYST (Moz-Ybf2/Sas3-Sas2-Tip60) family of
histone acetyltransferases (HATs), is the human ortholog of the Drosophila males absent on …