Pubertal mammary gland development is a key determinant of adult mammographic density

AG Ghadge, P Dasari, J Stone, EW Thompson… - Seminars in Cell & …, 2021 - Elsevier
Mammographic density refers to the radiological appearance of fibroglandular and adipose
tissue on a mammogram of the breast. Women with relatively high mammographic density …

Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood

B Novakovic, S Lewis, J Halliday, J Kennedy… - Nature …, 2019 - nature.com
More than 7 million individuals have been conceived by Assisted Reproductive
Technologies (ART) and there is clear evidence that ART is associated with a range of …

[HTML][HTML] The Mechanisms and Application Value of Postbiotics in Caries Prevention and Management

X Jiang, M Lin, P Xiao, Z Zhou… - Oral Health & …, 2024 - pmc.ncbi.nlm.nih.gov
Dental caries, one of the most prevalent diseases globally, affects individuals throughout
their lifetimes. Recently, researchers have increasingly focused on postbiotics for caries …

How does socio-economic position (SEP) get biologically embedded? A comparison of allostatic load and the epigenetic clock (s)

C McCrory, G Fiorito, CN Cheallaigh, S Polidoro… - …, 2019 - Elsevier
Individuals of lower socio-economic position (SEP) carry a heavier burden of disease and
morbidity and live shorter lives on average compared with their more advantaged …

Genetic and environmental causes of variation in epigenetic aging across the lifespan

S Li, TL Nguyen, EM Wong, PA Dugué, GS Dite… - Clinical …, 2020 - Springer
Background DNA methylation-based biological age (DNAm age) is an important biomarker
for adult health. Studies in specific age ranges have found widely varying results about its …

[HTML][HTML] Wildfire-related PM2. 5 and DNA methylation: An Australian twin and family study

R Xu, S Li, Y Wu, X Yue, EM Wong, MC Southey… - Environment …, 2023 - Elsevier
Background Wildfire-related fine particulate matter (PM 2.5) has many adverse health
impacts, but its impacts on human epigenome are unknown. We aimed to evaluate the …

Early life affects late-life health through determining DNA methylation across the lifespan: A twin study

S Li, Z Ye, KA Mather, TL Nguyen, GS Dite… - …, 2022 - thelancet.com
Background Previous findings for the genetic and environmental contributions to DNA
methylation variation were for limited age ranges only. We investigated the lifespan …

Brain aging differs with cognitive ability regardless of education

KB Walhovd, L Nyberg, U Lindenberger, IK Amlien… - Scientific reports, 2022 - nature.com
Higher general cognitive ability (GCA) is associated with lower risk of neurodegenerative
disorders, but neural mechanisms are unknown. GCA could be associated with more cortical …

Epigenetic clocks and allostatic load reveal potential sex-specific drivers of biological aging

C McCrory, G Fiorito, S McLoughlin… - The Journals of …, 2020 - academic.oup.com
Allostatic load (AL) and epigenetic clocks both attempt to characterize the accelerated aging
of biological systems, but at present it is unclear whether these measures are …

Developmental tuning of epigenetic clock

A Vaiserman - Frontiers in genetics, 2018 - frontiersin.org
Research in the field of gerontology has traditionally focused on later life stages. There is
increasing evidence, however, that both the rate of age-related functional decline and the …