Infections with flaviviruses, such as dengue, West Nile virus and the recently re-emerging
Zika virus, are an increasing and probably lasting global risk. This Review summarizes and …

Membrane association is a hallmark of the genome replication of positive-strand RNA
viruses [(+) RNA viruses]. All well-studied (+) RNA viruses remodel host membranes and …

Coronavirus replication is associated with intracellular membrane rearrangements in
infected cells, resulting in the formation of double-membrane vesicles (DMVs) and other …

Flaviviruses are emerging arthropod-borne pathogens that cause life-threatening diseases
such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …

We describe the first comprehensive analysis of the midgut metabolome of Aedes aegypti,
the primary mosquito vector for arboviruses such as dengue, Zika, chikungunya and yellow …

Viruses manipulate cellular lipids and membranes at each stage of their life cycle. This
includes lipid-receptor interactions, the fusion of viral envelopes with cellular membranes …

Highlights•+ RNA viruses build membranous VRCs.•+ RNA viruses rewire cellular lipid
metabolism to build VRCs.•VRC structure and formation mechanisms differ between …

Flaviviruses are enveloped, positive-sensed single-stranded RNA viruses that remodel host
membranes, incorporating both viral and host factors facilitating viral replication. In this …

Flaviviruses are positive-sense single-stranded RNA viruses that pose a considerable threat
to human health. Flaviviruses replicate in compartmentalized replication organelles derived …

Ceramide is a lipid messenger at the heart of sphingolipid metabolism. In concert with its
metabolizing enzymes, particularly sphingomyelinases, it has key roles in regulating the …