Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies
LA Silva, TS Dermody - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal
inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and …
inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and …
Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen
Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein
The multifunctional nucleocapsid (N) protein in SARS-CoV-2 binds the~ 30 kb viral RNA
genome to aid its packaging into the 80–90 nm membrane-enveloped virion. The N protein …
genome to aid its packaging into the 80–90 nm membrane-enveloped virion. The N protein …
Virus-host interactome and proteomic survey reveal potential virulence factors influencing SARS-CoV-2 pathogenesis
J Li, M Guo, X Tian, X Wang, X Yang, P Wu, C Liu… - Med, 2021 - cell.com
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a global public health …
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a global public health …
Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to …
disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to …
Liquid–liquid phase separation by intrinsically disordered protein regions of viruses: Roles in viral life cycle and control of virus–host interactions
Intrinsically disordered proteins (IDPs) are unable to adopt a unique 3D structure under
physiological conditions and thus exist as highly dynamic conformational ensembles. IDPs …
physiological conditions and thus exist as highly dynamic conformational ensembles. IDPs …
Translation inhibition and stress granules in the antiviral immune response
C McCormick, DA Khaperskyy - Nature Reviews Immunology, 2017 - nature.com
Efficient viral gene expression is threatened by cellular stress response programmes that
rapidly reprioritize the translation machinery in response to varied environmental assaults …
rapidly reprioritize the translation machinery in response to varied environmental assaults …
Porcine epidemic diarrhea virus: An updated overview of virus epidemiology, virulence variation patterns and virus–host interactions
Y Zhang, Y Chen, J Zhou, X Wang, L Ma, J Li, L Yang… - Viruses, 2022 - mdpi.com
The porcine epidemic diarrhea virus (PEDV) is a member of the coronavirus family, causing
deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant …
deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant …
Alphavirus RNA synthesis and non-structural protein functions
JC Rupp, KJ Sokoloski… - Journal of General …, 2015 - microbiologyresearch.org
The members of the genus Alphavirus are positive-sense RNA viruses, which are
predominantly transmitted to vertebrates by a mosquito vector. Alphavirus disease in …
predominantly transmitted to vertebrates by a mosquito vector. Alphavirus disease in …
[HTML][HTML] A proposed role for the SARS‐CoV‐2 nucleocapsid protein in the formation and regulation of biomolecular condensates
SM Cascarina, ED Ross - The FASEB Journal, 2020 - ncbi.nlm.nih.gov
To date, the recently discovered SARS‐CoV‐2 virus has afflicted> 6.9 million people
worldwide and disrupted the global economy. Development of effective vaccines or …
worldwide and disrupted the global economy. Development of effective vaccines or …