The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Long noncoding RNAs are involved in epigenetic gene modification, including binding to the
chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in …

Circular RNAs (circRNAs) are abundantly expressed in the haematopoietic compartment,
but knowledge on their diversity among blood cell types is still limited. Nevertheless …

PVT1, a long non-coding RNA has been implicated in a variety of human cancers. Recent
advancements have led to increasing discovery of the critical roles of PVT1 in cancer …

Non coding RNAs (ncRNAs) have emerged as regulators of human carcinogenesis by
affecting the expression of key tumor suppressor genes and oncogenes. They are divided …

Leukemia is a common malignant cancer of the hematopoietic system, whose pathogenesis
has not been fully elucidated. Long noncoding RNAs (lncRNAs) are transcripts longer than …

Lymphoid cells play a critical role in the immune system, which includes three subgroups of
T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in …

The coding regions account for only a small part of the human genome, and the remaining
vast majority of the regions generate large amounts of non-coding RNAs. Although non …

NGS technologies and bioinformatics tools allow the rapid identification of chimeric
transcripts in cancer. More than 40,000 fusions are so far reported in the literature; however …

The early detection and diagnosis of cancer is critical to optimize the treatment and
management of cancer patients. Typical methods such as imaging and tissue biopsy are …