Sensitivity to vaccines, therapeutic antibodies, and viral entry inhibitors and advances to counter the SARS-CoV-2 Omicron variant
H Zhou, M Møhlenberg, JC Thakor… - Clinical microbiology …, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) keeps evolving and
mutating into newer variants over time, which gain higher transmissibility, disease severity …
mutating into newer variants over time, which gain higher transmissibility, disease severity …
Understanding mutations in human SARS-CoV-2 spike glycoprotein: a systematic review & meta-analysis
Genetic variant (s) of concern (VoC) of SARS-CoV-2 have been emerging worldwide due to
mutations in the gene encoding spike glycoprotein. We performed comprehensive analyses …
mutations in the gene encoding spike glycoprotein. We performed comprehensive analyses …
The 2022 Nucleic Acids Research database issue and the online molecular biology database collection
DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …
87 papers reporting on new databases and 85 updates from resources previously published …
CoVEffect: interactive system for mining the effects of SARS-CoV-2 mutations and variants based on deep learning
Abstract Background Literature about SARS-CoV-2 widely discusses the effects of variations
that have spread in the past 3 years. Such information is dispersed in the texts of several …
that have spread in the past 3 years. Such information is dispersed in the texts of several …
Need of booster vaccine doses to counteract the emergence of SARS-CoV-2 variants in the context of the Omicron variant and increasing COVID-19 cases: An update
The emergence of different variants of SARS-CoV-2, including the Omicron (B. 1.1. 529)
variant in November 2021, has resulted in a continuous major health concern at a global …
variant in November 2021, has resulted in a continuous major health concern at a global …
Key substitutions in the spike protein of SARS-CoV-2 variants can predict resistance to monoclonal antibodies, but other substitutions can modify the effects
S Lusvarghi, W Wang, R Herrup… - Journal of …, 2022 - Am Soc Microbiol
Mutations in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants can compromise the effectiveness of therapeutic antibodies. Most clinical …
CoV-2) variants can compromise the effectiveness of therapeutic antibodies. Most clinical …
[HTML][HTML] Applying the digital data and the bioinformatics tools in SARS-CoV-2 research
M Tan, J Xia, H Luo, G Meng, Z Zhu - Computational and Structural …, 2023 - Elsevier
Bioinformatics has been playing a crucial role in the scientific progress to fight against the
pandemic of the coronavirus disease 2019 (COVID-19) caused by the severe acute …
pandemic of the coronavirus disease 2019 (COVID-19) caused by the severe acute …
Impact of vaccination on SARS-CoV-2 evolution and immune escape variants
Vaccines and host genetic factors can influence the SARS-CoV-2 evolution and emergence
of new variants. Even vaccinated cases get affected as virus continues to evolve, raising …
of new variants. Even vaccinated cases get affected as virus continues to evolve, raising …
[HTML][HTML] Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA
virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the …
virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the …
Discrimination of SARS-CoV-2 omicron variant and its lineages by rapid detection of immune-escape mutations in spike protein RBD using asymmetric PCR-based …
X Kong, P Gao, Y Jiang, L Lu, M Zhao, Y Liu, G Deng… - Virology Journal, 2023 - Springer
Abstract Background The SARS-CoV-2 Omicron strain has multiple immune-escape
mutations in the spike protein receptor-binding domain (RBD). Rapid detection of these …
mutations in the spike protein receptor-binding domain (RBD). Rapid detection of these …