Lactic acid bacteria in relieving constipation: mechanism, clinical application, challenge, and opportunity

T Zhang, W Liu, H Lu, T Cheng, L Wang… - Critical Reviews in …, 2025 - Taylor & Francis
Constipation is a prevalent gastrointestinal symptom that can considerably affect a patients'
quality of life. Although several drugs have been used to treat constipation, they are …

[HTML][HTML] The role of short chain fatty acids in irritable bowel syndrome

W Jiang, J Wu, S Zhu, L Xin, C Yu… - Journal of …, 2022 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is characterized
by abdominal pain and disordered bowel habits. The etiology of IBS is multifactorial …

A review of the impact of maternal prenatal stress on offspring microbiota and metabolites

V Yeramilli, R Cheddadi, J Shah, K Brawner, C Martin - Metabolites, 2023 - mdpi.com
Maternal prenatal stress exposure affects the development of offspring. We searched for
articles in the PubMed database and reviewed the evidence for how prenatal stress alters …

Atractyloside-A ameliorates spleen deficiency diarrhea by interfering with TLR4/MyD88/NF-κB signaling activation and regulating intestinal flora homeostasis

J Xu, C Liu, K Shi, X Sun, C Song, K Xu, Y Liu - International …, 2022 - Elsevier
Purpose Spleen deficiency diarrhea (SDD) is one of the most common types of diarrhea and
is linked to intestinal barrier dysfunction and intestinal flora disorders. Atractyloside-A (AA) is …

Calcium image analysis in the moving gut

BB Barth, ER Redington, N Gautam… - …, 2023 - Wiley Online Library
Background The neural control of gastrointestinal muscle relies on circuit activity whose
underlying motifs remain limited by small‐sample calcium imaging recordings confounded …

Relaxing the “second brain”: nutrients and bioactive compounds as a therapeutic and preventive strategy to alleviate oxidative stress in the enteric nervous system

PP Almeida, AL Tavares-Gomes… - Nutrition …, 2022 - academic.oup.com
The enteric nervous system (ENS) regulates several functional and immunological
processes in the gastrointestinal tract. However, some diseases can disrupt the ENS …

Optogenetic activation of the distal colon epithelium engages enteric nervous system circuits to initiate motility patterns

SA Najjar, BS Edwards, KM Albers… - American Journal …, 2021 - journals.physiology.org
Digestive functions of the colon depend on sensory-motor reflexes in the enteric nervous
system (ENS), initiated by intrinsic primary afferent neurons (IPANs). IPAN terminals project …

Is the enteric nervous system a lost piece of the gut-kidney axis puzzle linked to chronic kidney disease?

PP Almeida, ML Brito, B Thomasi, D Mafra, D Fouque… - Life Sciences, 2024 - Elsevier
The enteric nervous system (ENS) regulates numerous functional and immunological
attributes of the gastrointestinal tract. Alterations in ENS cell function have been linked to …

Fecal supernatants from dogs with idiopathic epilepsy activate enteric neurons

K Elfers, A Watanangura, P Hoffmann… - Frontiers in …, 2024 - frontiersin.org
Introduction Alterations in the composition and function of the gut microbiome have been
reported in idiopathic epilepsy (IE), however, interactions of gut microbes with the enteric …

Association between gut microbiota and Hirschsprung disease: a bidirectional two-sample Mendelian randomization study

W Liu, H Yan, W Jia, J Huang, Z Fu, W Xu… - Frontiers in …, 2024 - frontiersin.org
Background Several studies have pointed to the critical role of gut microbiota (GM) and their
metabolites in Hirschsprung disease (HSCR) pathogenesis. However, the detailed causal …