[HTML][HTML] Parvalbumin as a sex-specific target in Alzheimer's disease research, A mini-review

DJ Terstege, JR Epp - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia, and both the incidence of
this disease and its associated cognitive decline disproportionally effect women. While the …

Effects of prenatal opioid exposure on synaptic adaptations and behaviors across development

SC Simmons, GG Grecco, BK Atwood, FS Nugent - Neuropharmacology, 2023 - Elsevier
In this review, we focus on prenatal opioid exposure (POE) given the significant concern for
the mental health outcomes of children with parents affected by opioid use disorder (OUD) in …

Rodent models for mood disorders–understanding molecular changes by investigating social behavior

PR Reinhardt, CDC Theis, G Juckel, N Freund - Biological Chemistry, 2023 - degruyter.com
Mood disorders, including depressive and bipolar disorders, are the group of psychiatric
disorders with the highest prevalence and disease burden. However, their pathophysiology …

Points of divergence on a bumpy road: early development of brain and immune threat processing systems following postnatal adversity

HC Brenhouse - Molecular psychiatry, 2023 - nature.com
Lifelong indices of maladaptive behavior or illness often stem from early physiological
aberrations during periods of dynamic development. This is especially true when …

Maternal separation and its developmental consequences on anxiety and parvalbumin interneurons in the amygdala

M Abraham, K Schmerder, M Hedtstück… - Journal of Neural …, 2023 - Springer
The early postnatal period represents an exceptionally vulnerable phase for the
development of neurobiological alterations, aberrant behavior, and psychiatric disorders …

Early life adversity impaired dorsal striatal synaptic transmission and behavioral adaptability to appropriate action selection in a sex-dependent manner

G de Carvalho, S Khoja, MT Haile… - Frontiers in Synaptic …, 2023 - frontiersin.org
Early life adversity (ELA) is a major health burden in the United States, with 62% of adults
reporting at least one adverse childhood experience. These experiences during critical …

Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala

R Sagi, M Chakraborty, M Bogdanovic, H Asraf… - Behavioral and Brain …, 2024 - Springer
Background Mood disorders, particularly depression and anxiety, are associated with zinc
dyshomeostasis and aberrant GABAergic signaling. Activation of ZnR/GPR39 by synaptic …

Non-human contributions to personality neuroscience–from fish through primates. An introduction to the special issue

YV Lages, N McNaughton - Personality Neuroscience, 2022 - cambridge.org
The most fundamental emotional systems that show trait control are evolutionarily old and
extensively conserved. Psychology in general has benefited from non-human neuroscience …

Differential impact of adolescent or adult stress on behavior and cortical parvalbumin interneurons and perineuronal nets in male and female mice

T Santos-Silva, BK Souza, DAE Colodete… - International Journal …, 2024 - academic.oup.com
Background Stress has become a common public health concern, contributing to the rising
prevalence of psychiatric disorders. Understanding the impact of stress considering critical …

[HTML][HTML] Effects of Early Stress Exposure on Anxiety-like Behavior and MORC1 Expression in Rats

A Mundorf, N Freund - Biomolecules, 2024 - mdpi.com
Exposure to stress during early and late childhood can lead to long-lasting neurobiological
and behavioral impairments. Although sensitive periods for stress exposure are well …