Cancer continues to pose a significant global health challenge, as evidenced by the
increasing incidence rates and high mortality rates, despite the advancements made in …

Metformin, as the preferred antihyperglycemic drug for type 2 diabetes, has been found to
have a significant effect in inhibiting tumor growth in recent years. However, metformin alone …

Cyclophosphamide (CYP), methotrexate (MTX), and 5-fluorouracil (5-FU) are extensively
utilized in the therapeutic management of various malignancies. It is noteworthy, however …

Aims Clinical data demonstrate that metformin exhibits antiproliferative, proapoptotic and
antimetastatic actions. Here, correlative molecular studies were undertaken to determine the …

Globally, breast cancer represents the most common cancer and the primary cause of death
by cancer in women. Lipids are crucial in human physiology, serving as vital energy …

Diabetes mellitus (DM) is a significant risk factor for various cancers, with the impact of anti-
diabetic therapies on cancer progression differing across malignancies. Among these …

Metformin is an attractive candidate drug among all the repurposed drugs for cancer.
Extensive preclinical and clinical research has evaluated its efficacy in cancer therapy …

Over the last several decades, a growing body of research has investigated the potential to
repurpose the anti-diabetic drug metformin for breast cancer prevention and/or treatment …

Cancer and cardiovascular disease represent the two leading causes of morbidity and
mortality worldwide. Women continue to enjoy a greater life expectancy than men. However …

Cytotoxic interface dermatitis (CID) is a pattern reaction predominantly at the dermo-
epidermal junction that encapsulates numerous chronic non-communicable inflammatory …