Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …

In an era where the pipeline of new antibiotic development is drying up, the continuous rise
of multi-drug resistant (MDR) and extensively drug resistant (XDR) bacteria are genuine …

Multi-drug-resistant bacteria are becoming more prevalent, and treating these bacteria is
becoming a global concern. One alternative approach to combat bacterial resistance is to …

Antimicrobial peptides (AMPs) have been identified as a potentially new class of antibiotics
to combat bacterial resistance to conventional drugs. The design of de novo AMPs with high …

Global rise of infections and deaths caused by drug-resistant bacterial pathogens are
among the unmet medical needs. In an age of drying pipeline of novel antibiotics to treat …

Arthropod venoms feature the presence of cytolytic peptides believed to act synergetically
with neurotoxins to paralyze prey or deter aggressors. Many of them are linear, ie, lack …

Dental caries and periodontitis are common bacterial mouth infections. As a potentially
attractive substitute for conventional antibiotics, antimicrobial peptides have been widely …

Objectives. Interactions between the host and gut microbial community contribute to the
pathogenesis of Crohn's disease (CD). In this study, we aimed to detect lipopolysaccharide …

Currently, viable antibiotics available to mitigate infections caused by drug-resistant Gram-
negative bacteria are highly limited. Thanatin, a 21-residue-long insect-derived antimicrobial …