A central function of the vascular endothelium is to serve as a barrier between the blood and
the surrounding tissue of the body. At the same time, solutes and cells have to pass the …

Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …

The current tumour-node-metastasis (TNM) staging system alone cannot provide adequate
information for prognosis and adjuvant chemotherapy benefits in patients with gastric cancer …

Metastasis is a complex, multistep process responsible for> 90% of cancer-related deaths. In
addition to genetic and external environmental factors, the physical interactions of cancer …

The use of CEA as a prognostic and predictive marker in patients with lung cancer is widely
debated. The aim of this review was to evaluate the results from studies made on this …

Matrix metalloproteinases are versatile endopeptidases with many different functions in the
body in health and disease. In the brain, matrix metalloproteinases are critical for tissue …

Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

Formation of distant metastases is by far the most common cause of cancer-related deaths.
The process of metastasis formation is complex, and within this complex process the …

By gating the traffic of molecules and cells across the vessel wall, endothelial cells play a
central role in regulating cardiovascular functions and systemic homeostasis and in …

Active targeting in cancer nanomedicine, for improved delivery of agents and diagnose, has
been reviewed as a successful way for facilitating active uptake of theranostic agents by the …