Comparative efficacy, safety and benefit/risk of alerting agents for excessive daytime sleepiness in patients with obstructive sleep apnoea: a network meta-analysis

JL Pépin, P Lehert, RB Messaoud… - …, 2024 - thelancet.com
Background Obstructive sleep apnoea (OSA) is a common chronic respiratory disease
associated with a high burden of disabilities related to sleepiness and reduced quality of life …

Evaluating Pharmacological Treatments for Excessive Daytime Sleepiness in Obstructive Sleep Apnea: A Comprehensive Network Meta-Analysis and Systematic …

SS Neshat, A Heidari, M Henriquez-Beltran… - Sleep Medicine …, 2024 - Elsevier
Obstructive sleep apnea (OSA) is associated with excessive daytime sleepiness (EDS).
Pharmacotherapy offers a potential treatment approach for EDS in OSA patients. This …

Obstructive sleep apnea phenotypes eligible for pharmacological treatment

M Bruyneel - Frontiers in Sleep, 2023 - frontiersin.org
Obstructive sleep apnea (OSA) is a common disorder. Its prevalence is increasing
worldwide, partially due to increasing rates of obesity, and OSA has a well-documented …

[HTML][HTML] Morning resting hypothalamus-dorsal striatum connectivity predicts individual differences in diurnal sleepiness accumulation

T Mao, B Guo, P Quan, Y Deng, Y Chai, J Xu, C Jiang… - NeuroImage, 2024 - Elsevier
While the significance of obtaining restful sleep at night and maintaining daytime alertness is
well recognized for human performance and overall well-being, substantial variations exist …

Effectiveness of orthognathic surgery by maxillomandibular advancement combined with soft tissue surgery as curative treatment for obstructive sleep apnea …

L Bègue, G Raoul, F Barry, R Nicot - Journal of Stomatology, Oral and …, 2025 - Elsevier
Abstract Objective/Background The aim of this study was to compare the efficacy of
orthognathic surgery combined with soft tissue surgery with that of soft tissue surgery alone …

[HTML][HTML] Excessive daytime sleepiness in obstructive sleep apnea: Indirect treatment comparison of wake-promoting agents in patients adherent/nonadherent to …

Y Wang, W Zhang, H Ye, Y Xiao - Sleep Medicine Reviews, 2024 - Elsevier
There remains an unmet need for a targeted treatment to address residual excessive
daytime sleepiness (EDS) in patients with obstructive sleep apnea (OSA) after primary …

Solriamfetol: A Review in Excessive Daytime Sleepiness Associated with Narcolepsy and Obstructive Sleep Apnoea

SM Hoy - CNS drugs, 2023 - Springer
Solriamfetol (SUNOSI®) is an oral selective dopamine and norepinephrine reuptake
inhibitor approved in the EU and the USA for improving wakefulness in adults with excessive …

Development and application of a machine learning-based predictive model for obstructive sleep apnea screening

K Liu, S Geng, P Shen, L Zhao, P Zhou, W Liu - Frontiers in big Data, 2024 - frontiersin.org
Objective To develop a robust machine learning prediction model for the automatic
screening and diagnosis of obstructive sleep apnea (OSA) using five advanced algorithms …

Recovery Mimicking “Ideal” CPAP Adherence Does Not Improve Wakefulness or Cognition in Chronic Murine Models of OSA: Effect of Wake-Promoting Agents

M Badran, C Puech, MB Barrow, AR Runion… - Archivos de …, 2023 - Elsevier
Introduction Obstructive sleep apnea (OSA) is a chronic condition characterized by
intermittent hypoxia (IH) and sleep fragmentation (SF). OSA can induce excessive daytime …

ChatGPT for assessing risk of bias of randomized trials using the RoB 2.0 tool: A methods study

T Pitre, T Jassal, JR Talukdar, M Shahab, M Ling… - medRxiv, 2023 - medrxiv.org
Background Internationally accepted standards for systematic reviews necessitate
assessment of the risk of bias of primary studies. Assessing risk of bias, however, can be …