Bronchial asthma is a chronic inflammatory disease in which bronchial wall remodelling
plays a significant role. This phenomenon is related to enhanced proliferation of airway …

Atopic dermatitis, allergic rhinitis, and asthma are atopic diseases that develop on a complex
genetic background, the so-called atopic diathesis. Although they target different organs, in …

Diagnosis early in life, sensitization, asthma endotypes, monitoring of disease and treatment
progression are key motivations for the exploration of biomarkers for allergic rhinitis and …

The cytokine interleukin 13 (IL-13) is a major effector molecule for T-helper type 2
inflammation and is pathogenic in allergic diseases such as asthma. The effects of IL-13 are …

The cytokines interleukin 13 and 4 share a common heterodimeric receptor and are
important modulators of peripheral allergic reactions. Produced primarily by T-helper type 2 …

Background Allergic asthma is a complex disorder characterized by local and systemic T
helper type 2‐cell responses such as the production of IL‐13, a cytokine associated with the …

Background Severe asthma is characterized by elevated levels of pro‐inflammatory
cytokines and neutrophilic inflammation in the airways. Blood cytokines, markers of …

Background STAT 3 drives development of Th17 cells and cytokine production by Th2 and
Th17 cells, which contribute to asthma. Alternative asthma treatments are needed …

Asthma is a chronic inflammatory disease of the airways in which immunoglobulin E (IgE)
plays a key role by activating a variety of inflammatory cells through interactions with FcɛRI …

Neutrophil extracellular traps (NETs) are intricate, DNA-based, web-like structures adorned
with cytotoxic proteins. They play a crucial role in antimicrobial defense but are also …