Coumarin-based fluorogenic probes have emerged as preferred imaging tools to real-time
and non-invasively monitor target analyte (s) in biological systems, due to their inherent …

Neurodegenerative diseases are debilitating disorders that feature progressive and
selective loss of function or structure of anatomically or physiologically associated neuronal …

Fluorescence imaging in the second near‐infrared (NIR‐II) window holds great promise for
in vivo visualization of amyloid‐β (Aβ) pathology, which can facilitate characterization and …

Amyloids are a broad class of proteins and peptides that can misfold and assemble into long
unbranched fibrils with a cross-β conformation. These misfolding and aggregation events …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a major
contributor to dementia cases worldwide. AD is clinically characterized by learning, memory …

Fibrillar protein aggregates are characteristic of neurodegenerative diseases but represent
difficult targets for ligand design, because limited structural information about the binding …

It has been speculated that both the intracellular viscosity and H2O2 level in Alzheimer's
disease (AD) brains are higher than that in healthy brains, but direct evidence from living …

Human civilization has witnessed the use of materials-derived from biomolecules of plants
and animal origin for biomedical applications since ancient era. In recent years, precision …

The accumulation of amyloid fibrils is characteristic of neurodegenerative diseases such as
Alzheimer's disease (AD) and Parkinson's disease. Detecting these fibrils with fluorescent or …

Single-atom nanozymes are a class of nanozymes with attractive enzyme-like activities.
They usually mimic oxidoreductases and lack other types of enzyme-like activities. Hence …