Functions of ROS in macrophages and antimicrobial immunity

M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Modulation of macrophage immunometabolism: A new approach to fight infections

T Gauthier, W Chen - Frontiers in Immunology, 2022 - frontiersin.org
Macrophages are essential innate immune cells that contribute to host defense during
infection. An important feature of macrophages is their ability to respond to extracellular cues …

One health approach to leishmaniases: understanding the disease dynamics through diagnostic tools

A Hong, RA Zampieri, JJ Shaw, LM Floeter-Winter… - Pathogens, 2020 - mdpi.com
Leishmaniases are zoonotic vector-borne diseases caused by protozoan parasites of the
genus Leishmania that affect millions of people around the globe. There are various clinical …

[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

[HTML][HTML] Deep learning for microscopic examination of protozoan parasites

C Zhang, H Jiang, H Jiang, H Xi, B Chen, Y Liu… - Computational and …, 2022 - Elsevier
The infectious and parasitic diseases represent a major threat to public health and are
among the main causes of morbidity and mortality. The complex and divergent life cycles of …

Leishmania Immunity: Advancing Immunotherapy and Vaccine Development

NM Ikeogu, GN Akaluka, CA Edechi, ES Salako… - Microorganisms, 2020 - mdpi.com
Parasitic diseases still constitute a major global health problem affecting billions of people
around the world. These diseases are capable of becoming chronic and result in high …

The pathogenicity and virulence of Leishmania-interplay of virulence factors with host defenses

AK Gupta, S Das, M Kamran, SA Ejazi, N Ali - Virulence, 2022 - Taylor & Francis
Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …

Immunotherapy and immunochemotherapy in combating visceral leishmaniasis

G Yadagiri, A Singh, K Arora, SL Mudavath - Frontiers in Medicine, 2023 - frontiersin.org
Visceral leishmaniasis (VL), a vector-borne disease, is caused by an obligate
intramacrophage, kinetoplastid protozoan parasite of the genus Leishmania. Globally, VL is …

Cutaneous leishmaniasis: the complexity of host's effective immune response against a polymorphic parasitic disease

Á Gabriel, A Valério-Bolas… - Journal of …, 2019 - Wiley Online Library
This review is aimed at providing a comprehensive outline of the immune response
displayed against cutaneous leishmaniasis (CL), the more common zoonotic infection …

Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies

H Yasmin, A Adhikary, MN Al-Ahdal, S Roy, U Kishore - Immuno, 2022 - mdpi.com
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …