Routine diagnostics and treatment monitoring of brain tumors is usually based on contrast-
enhanced MRI. However, the capacity of conventional MRI to differentiate tumor tissue from …

Positron emission tomography (PET) is an imaging technology that can detect and
characterize tumors based on their molecular and biochemical properties, such as altered …

Glioblastoma (GBM) is characterized by extremely poor prognoses, despite the use of gross
surgical resection, alkylating chemotherapeutic agents, and radiotherapy. Evidence …

A previous review published in 2012 demonstrated the role of clinical PET for diagnosis and
management of brain tumors using mainly FDG, amino acid tracers, and 18 F …

Glioblastoma (GBM) is the most common primary adult intracranial malignancy and carries a
dismal prognosis despite an aggressive multimodal treatment regimen that consists of …

Malignant cells are commonly characterised by being capable of invading tissue, growing
self-sufficiently and uncontrollably, being insensitive to apoptosis induction and controlling …

Although rare, glioblastomas account for the majority of primary brain lesions, with a
dreadful prognosis. Magnetic resonance imaging (MRI) is currently the imaging method …

The fields of tumor metabolism and immune oncology have both independently received
considerable attention over the last several years. The majority of research in tumor …

Background Although glioblastomas are heterogeneous brain-infiltrating tumors, their
treatment is mostly focused on the contrast-enhancing tumor mass. In this study, we …

Immunotherapy with checkpoint inhibitors demonstrates impressive improvements in the
treatment of several types of cancer. Unfortunately, not all patients respond to therapy while …