From Biobanking to Personalized Medicine: the journey of the Estonian Biobank

L Milani, M Alver, S Laur, S Reisberg, T Haller… - medRxiv, 2024 - medrxiv.org
Large biobanks have set a new standard for research and innovation in human genomics
and implementation of personalised medicine. The Estonian Biobank was founded a quarter …

Relevance, strategies, and added value of mouse models in androgenetics

V Singh, JC Schimenti - Andrology, 2024 - Wiley Online Library
Abstract Background Male Infertility is a prevalent condition worldwide, and a substantial
fraction of cases are thought to have a genetic basis. Investigations into the responsible …

Inherited infertility: Mapping loci associated with impaired female reproduction

S Ruotsalainen, J Karjalainen, M Kurki… - The American Journal of …, 2024 - cell.com
Female infertility is a common and complex health problem affecting millions of women
worldwide. While multiple factors can contribute to this condition, the underlying cause …

Genome-wide analysis identifies 66 variants underlying anatomical variation in human neuroendocrine structures and reveals links to testosterone

H Currant, C Arthofer, T Ferreira, G Douaud, B Hill… - medRxiv, 2024 - medrxiv.org
The hypothalamus, pituitary gland and olfactory bulbs are neuroanatom-ical structures key
to the regulation of the endocrine system. Variation in their anatomy can affect the function of …