Crossing the blood-brain barrier: advances in nanoparticle technology for drug delivery in neuro-oncology
The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …
Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques
Owing to their tunable properties, controllable degradation, and ability to protect labile
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
Nanotechnology in ovarian cancer: Diagnosis and treatment
To overcome the drawbacks of conventional delivery, this review spotlights a number of
nanoscale drug delivery systems, including nanoparticles, liposomes, nano micelles …
nanoscale drug delivery systems, including nanoparticles, liposomes, nano micelles …
The ascension of nanosponges as a drug delivery carrier: preparation, characterization, and applications
K Tiwari, S Bhattacharya - Journal of Materials Science: Materials in …, 2022 - Springer
Nanosponges are nanosized drug carriers with a three-dimensional structure created by
crosslinking polymers. They have the advantage of being able to hold a wide range of drugs …
crosslinking polymers. They have the advantage of being able to hold a wide range of drugs …
Recent advances in nano delivery systems for blood-brain barrier (BBB) penetration and targeting of brain tumors
Gliomas constitute about 80% of brain tumors and have a meager two-year survival rate.
The treatment options available are very few because of poor prognosis and a lack of …
The treatment options available are very few because of poor prognosis and a lack of …
[HTML][HTML] Injectable thermoresponsive hydrogels as drug delivery system for the treatment of central nervous system disorders: A review
The central nervous system (CNS), consisting of the brain, spinal cord, and retina,
superintends to the acquisition, integration and processing of peripheral information to …
superintends to the acquisition, integration and processing of peripheral information to …
Polymeric nanoparticles in brain cancer therapy: A review of current approaches
Translation of novel therapies for brain cancer into clinical practice is of the utmost
importance as primary brain tumors are responsible for more than 200,000 deaths …
importance as primary brain tumors are responsible for more than 200,000 deaths …
Micro‐nanocarriers based drug delivery technology for blood‐brain barrier crossing and brain tumor targeting therapy
L Wang, Y Shi, J Jiang, C Li, H Zhang, X Zhang… - Small, 2022 - Wiley Online Library
The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …
Injectable thermosensitive hydrogel containing erlotinib‐loaded hollow mesoporous silica nanoparticles as a localized drug delivery system for NSCLC therapy
X Zhou, X He, K Shi, L Yuan, Y Yang, Q Liu… - Advanced …, 2020 - Wiley Online Library
Erlotinib (ERT), oral administration agents, is one of the most pivotal targeted drugs in the
treatment of non‐small cell lung cancer (NSCLC); however, its poor solubility, low oral …
treatment of non‐small cell lung cancer (NSCLC); however, its poor solubility, low oral …
Rationally designed drug delivery systems for the local treatment of resected glioblastoma
Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high
recurrence and poor prognosis. The standard of care, surgical resection followed by …
recurrence and poor prognosis. The standard of care, surgical resection followed by …