Neurofibromatosis type 1 (NF1), also called von Recklinghausen disease or peripheral
neurofibromatosis, is a common autosomal dominant disorder characterised by multiple …

Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas typically
developing in the context of neurofibromatosis type 1 (NF-1). With the exception of surgical …

Von Recklinghausen neurofibromatosis (NF1) is a common autosomal dominant disorder
characterized by abnormalities in multiple tissues derived from the neural crest. No reliable …

Summary cDNA walking and sequencing have extended the open reading frame for the
neurofibromatosis type 1 gene (NFT). The new sequence now predicts 2485 amino acids of …

Three new neurofibromatosis type 1 (NFl) mutations have been detected and characterized.
Pulsed-field gel and Southern blot analyses reveal the mutations lo be deletions of 190, 40 …

Overlapping cDNA clones from the translocation breakpoint region (TBR) gene, recently
discovered at the neurofibromatosis type 1 locus and found to be interrupted by deletions …

Von Recklinghausen neurofibromatosis, or type 1 neurofibromatosis (NF1), is a common
autosomal dominant disorder characterized by abnormalities in multiple tissues derived from …

Individuals with neurofibromatosis type 1 (NF1) have an increased risk of developing benign
and malignant tumours. The NF1 gene is thought to be a tumour suppressor gene, yet no …

Abstract Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder characterized
by marked variation in clinical severity. To investigate the contribution to variability by genes …

Von Recklinghausen neurofibromatosis, or neurofibromatosis type 1 (NFI), affects
approximately 1 in 3500 individuals of all ethnic backgrounds. It is inherited as an autosomal …