Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
developing pathogen‐specific memory that confers immunological protection. Memory and …

Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …

The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that
starts from the genomic sequence of the pathogen and ends with a list of potential protein …

Vaccination is one of the most significant inventions in medicine. Reverse vaccinology (RV)
is a state-of-the-art technique to predict vaccine candidates from pathogen's genome (s). To …

Motivation Reverse vaccinology (RV) is a milestone in rational vaccine design, and machine
learning (ML) has been applied to enhance the accuracy of RV prediction. However, ML …

Reverse Vaccinology (RV) is a widely used approach to identify potential vaccine
candidates (PVCs) by screening the proteome of a pathogen through computational …

Antibiotic resistance (AR) is the resistance mechanism pattern in bacteria that evolves over
some time, thus protecting the bacteria against antibiotics. AR is due to bacterial evolution to …

Klebsiella pneumoniae is an opportunistic gram-negative bacterium that causes nosocomial
infection in healthcare settings. Despite the high morbidity and mortality rate associated with …

Moraxella catarrhalis (M. catarrhalis) is a Gram-negative bacterium that can cause serious
respiratory tract infections and middle ear infections in children and adults. M. catarrhalis …