Diagnosis and management of pituitary adenomas: a review

NA Tritos, KK Miller - Jama, 2023 - jamanetwork.com
Importance Pituitary adenomas are neoplasms of the pituitary adenohypophyseal cell
lineage and include functioning tumors, characterized by the secretion of pituitary hormones …

Complications of Cushing's syndrome: state of the art

R Pivonello, AM Isidori, MC De Martino… - The lancet Diabetes & …, 2016 - thelancet.com
Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and
excessive secretion of cortisol. The syndrome is associated with increased mortality and …

The treatment of Cushing's disease

R Pivonello, M De Leo, A Cozzolino… - Endocrine …, 2015 - academic.oup.com
Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome

M Fleseriu, BMK Biller, JW Findling… - The Journal of …, 2012 - academic.oup.com
Context: Cushing's syndrome (CS) is a disorder associated with significant morbidity and
mortality due to prolonged exposure to high cortisol concentrations. Objective: Our objective …

MANAGEMENT OF ENDOCRINE DISEASE: The burden of Cushing's disease: clinical and health-related quality of life aspects

RA Feelders, SJ Pulgar, A Kempel… - European journal of …, 2012 - academic.oup.com
Objective Cushing's disease (CD) is a rare endocrine disorder characterized by excess
secretion of ACTH due to a pituitary adenoma. Current treatment options are limited and …

Approach to the patient: diagnosis of Cushing syndrome

M Savas, S Mehta, N Agrawal… - The Journal of …, 2022 - academic.oup.com
Cushing syndrome results from supraphysiological exposure to glucocorticoids and is
associated with significant morbidity and mortality. The pathogenesis includes …

The medical treatment of Cushing's disease: effectiveness of chronic treatment with the dopamine agonist cabergoline in patients unsuccessfully treated by surgery

R Pivonello, MC De Martino… - The Journal of …, 2009 - academic.oup.com
Background: The role of dopamine agonists in the treatment of Cushing's disease (CD) has
been previously debated. Aim: The aim of this study was to evaluate the effectiveness of …

Neuropsychiatric disorders in Cushing's syndrome

R Pivonello, C Simeoli, MC De Martino… - Frontiers in …, 2015 - frontiersin.org
Endogenous Cushing's syndrome (CS), a rare endocrine disorder characterized by cortisol
hypersecretion, is associated with psychiatric and neurocognitive disorders. Major …

Cortisol assays and diagnostic laboratory procedures in human biological fluids

R Gatti, G Antonelli, M Prearo, P Spinella… - Clinical …, 2009 - Elsevier
The overview of cortisol physiology, action and pathology is achieved in relation to the
hypothalamic–pituitary–adrenal axis alteration by laboratory investigation. The …

Glucocorticoids and type 2 diabetes: from physiology to pathology

G Di Dalmazi, U Pagotto, R Pasquali… - Journal of nutrition …, 2012 - Wiley Online Library
Type 2 diabetes mellitus is the result of interaction between genetic and environmental
factors, leading to heterogeneous and progressive pancreatic β‐cell dysfunction …