VLDL Biogenesis and Secretion: it takes a village

W van Zwol, B van de Sluis, HN Ginsberg… - Circulation …, 2024 - Am Heart Assoc
The production and secretion of VLDLs (very-low-density lipoproteins) by hepatocytes has a
direct impact on liver fat content, as well as the concentrations of cholesterol and …

G protein-coupled receptor 146: new insights from genetics and model systems

U Tharehalli, A Rimbert - Current Opinion in Lipidology, 2024 - journals.lww.com
Here, we outline and deliberate on recent progress focused on: enhancing comprehension
of the effects of inhibiting GPR146 in humans through genetic instruments, evaluating the …

Identification of candidate genes and pathways associated with juvenile idiopathic arthritis by integrative transcriptome-wide association studies and mRNA …

R Feng, M Lu, C Yin, K Xu, L Liu, P Xu - Arthritis research & therapy, 2023 - Springer
Aim Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of
childhood, with genetic susceptibility and pathological processes such as autoimmunity and …

Elucidating the multifaceted roles of GPR146 in non-specific orbital inflammation: a concerted analytical approach through the prisms of bioinformatics and machine …

Z Wu, L Li, T Xu, Y Hu, X Peng, Z Zhang, X Yao… - Frontiers in …, 2024 - frontiersin.org
Background Non-specific Orbital Inflammation (NSOI) is a chronic idiopathic condition
marked by extensive polymorphic lymphoid infiltration in the orbital area. The integration of …