MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …

MicroRNAs (miRNAs) are important regulators of gene expression that bind complementary
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …

Within cells, soluble RNPs can switch states to coassemble and condense into liquid or solid
bodies. Although these phase transitions have been reconstituted in vitro, for endogenous …

Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

A population-based screen to determine the genetic frequency of myotonic dystrophy (DM)
is technically feasible but has not yet been performed on a large scale. The most ambitious …

Myotonic dystrophy is the most common type of muscular dystrophy in adults and is
characterised by progressive myopathy, myotonia, and multiorgan involvement. Two …

Myotonic dystrophy (DM) is the most common adult muscular dystrophy, characterized by
autosomal dominant progressive myopathy, myotonia and multiorgan involvement. To date …

Inhibition of muscleblind-like (MBNL) activity due to sequestration by microsatellite
expansion RNAs is a major pathogenic event in the RNA-mediated disease myotonic …

MicroRNAs (miRNAs) are small non-coding RNAs that play a critical role in regulating
diverse biological processes. Extracting functional insights from a list of miRNAs is …