Role of c-Jun N-terminal kinase (JNK) in obesity and type 2 diabetes

JHM Yung, A Giacca - Cells, 2020 - mdpi.com
Obesity has been described as a global epidemic and is a low-grade chronic inflammatory
disease that arises as a consequence of energy imbalance. Obesity increases the risk of …

[HTML][HTML] Effects of olive oil and its minor components on cardiovascular diseases, inflammation, and gut microbiota

G Marcelino, PA Hiane, KC Freitas, LF Santana, A Pott… - Nutrients, 2019 - mdpi.com
Olive oil is one of the main ingredients in the Mediterranean diet, being an important ally in
disease prevention. Its nutritional composition is comprised of mainly monounsaturated fatty …

The link between obesity, microbiota dysbiosis, and neurodegenerative pathogenesis

E Vamanu, SN Rai - Diseases, 2021 - mdpi.com
Current research in medicine in several parts of the world has attempted to establish a link
between the occurrence of neurodegenerative pathologies, microbiota dysbiosis, and the …

Adiponectin synthesis, secretion and extravasation from circulation to interstitial space

SC da Silva Rosa, M Liu, G Sweeney - Physiology, 2021 - journals.physiology.org
Adiponectin, an adipokine that circulates as multiple multimeric complexes at high levels in
serum, has antidiabetic, anti-inflammatory, antiatherogenic, and cardioprotective properties …

Cytokine profiling plays a crucial role in activating immune system to clear infectious pathogens

JL Muñoz-Carrillo, JF Contreras-Cordero… - Immune response …, 2018 - books.google.com
Pathogen infections are recognized by the immune system, which consists of two types of
responses: an innate immune response that recognizes pathogenassociated molecular …

Adipose tissue inflammation linked to obesity: A review of current understanding, therapies and relevance of phyto-therapeutics

CE Aruwa, S Sabiu - Heliyon, 2024 - cell.com
Obesity is a current global challenge affecting all ages and is characterized by the up-
regulated secretion of bioactive factors/pathways which result in adipose tissue inflammation …

Protective role of St. John's wort and its components hyperforin and hypericin against diabetes through inhibition of inflammatory signaling: Evidence from in vitro and …

M Novelli, P Masiello, P Beffy, M Menegazzi - International journal of …, 2020 - mdpi.com
Diabetes mellitus is a very common chronic disease with progressively increasing
prevalence. Besides the well-known autoimmune and inflammatory pathogenesis of type 1 …

Flavonoids in adipose tissue inflammation and atherosclerosis: one arrow, two targets

MM Fardoun, D Maaliki, N Halabi, R Iratni… - Clinical …, 2020 - portlandpress.com
Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in
addition to beverages such as tea and coffee. Flavonoids are emerging as potent …

Adipocyte differentiation between obese and lean conditions depends on changes in miRNA expression

Y Heo, H Kim, J Lim, SS Choi - Scientific Reports, 2022 - nature.com
Adipogenesis is the process by which precursor cells, preadipocytes (preACs), differentiate
into adipocytes (ACs). Here, we investigated differentially expressed miRNAs (DEMs) …

[HTML][HTML] Pathogenesis of periodontal disease

JL Muñoz-Carrillo, VE Hernández-Reyes… - … and adjunctive non …, 2019 - intechopen.com
Inflammation is a physiological response of the innate immune system against several
endogenous or exogenous stimuli. Inflammation begins with an acute pattern; however, it …