Roles and mechanisms of exosomal non-coding RNAs in human health and diseases
C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
MOGONET integrates multi-omics data using graph convolutional networks allowing patient classification and biomarker identification
To fully utilize the advances in omics technologies and achieve a more comprehensive
understanding of human diseases, novel computational methods are required for integrative …
understanding of human diseases, novel computational methods are required for integrative …
Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
Systematic review of miRNA as biomarkers in Alzheimer's disease
Currently there are 850,000 people with Alzheimer's disease in the UK, with an estimated
rise to 1.1 million by 2025. Alzheimer's disease is characterised by the accumulation of …
rise to 1.1 million by 2025. Alzheimer's disease is characterised by the accumulation of …
[HTML][HTML] exRNA atlas analysis reveals distinct extracellular RNA cargo types and their carriers present across human biofluids
To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …
[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders
MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood
L Cheng, RA Sharples, BJ Scicluna… - Journal of extracellular …, 2014 - Taylor & Francis
Introduction microRNA (miRNA) are small non-coding RNA species that are transcriptionally
processed in the host cell and released extracellularly into the bloodstream. Normally …
processed in the host cell and released extracellularly into the bloodstream. Normally …
Extracellular vesicles in neurodegenerative disease—pathogenesis to biomarkers
AG Thompson, E Gray, SM Heman-Ackah… - Nature Reviews …, 2016 - nature.com
To develop effective disease-modifying therapies for neurodegenerative diseases, reliable
markers of diagnosis, disease activity and progression are a research priority. The fact that …
markers of diagnosis, disease activity and progression are a research priority. The fact that …
Circular RNA (circRNA) in Alzheimer's disease (AD)
WJ Lukiw - Frontiers in genetics, 2013 - frontiersin.org
Circular RNAs (circRNAs) are a naturally occurring family of noncoding RNAs (ncRNAs)
highly represented in the eukaryotic transcriptome. Recently characterized, traditional …
highly represented in the eukaryotic transcriptome. Recently characterized, traditional …