The role of non-coding RNAs in oncology

FJ Slack, AM Chinnaiyan - Cell, 2019 - cell.com
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …

New insights into long noncoding RNAs and their roles in glioma

Z Peng, C Liu, M Wu - Molecular cancer, 2018 - Springer
Glioma is one of the most prevalent types of primary intracranial carcinoma with varying
malignancy grades I–IV and histological subtypes, including astrocytomas, glioblastoma …

[PDF][PDF] Retracted article

X Wang, W Xu, G Hu, S Xia, Z Sun… - Scientific …, 2021 - asp-eurasipjournals.springeropen …
With the in-depth development of the market economy and the acceleration of the process of
urbanization, a large number of people have poured into the city, and a large number of …

Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: A combinational approach for enhanced delivery of nanoparticles

M Norouzi, V Yathindranath, JA Thliveris, BM Kopec… - Scientific reports, 2020 - nature.com
Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …

Long noncoding RNAs as biomarkers in cancer

L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …

From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis

S Dhamija, S Diederichs - International journal of cancer, 2016 - Wiley Online Library
Metastasis is a multistep process that involves the dissemination of cells from the primary
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …

Long non‑coding RNA GAS5 in human cancer

X Yang, Z Xie, X Lei, R Gan - Oncology letters, 2020 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) constitute a group of> 200‑nucleotide ncRNA molecules.
lncRNAs regulate several cell functions, such as proliferation, apoptosis, invasion and …

Crosstalk between long noncoding RNAs and microRNAs in health and disease

AS Bayoumi, A Sayed, Z Broskova, JP Teoh… - International journal of …, 2016 - mdpi.com
Protein-coding genes account for only a small part of the human genome; in fact, the vast
majority of transcripts are comprised of non-coding RNAs (ncRNAs) including long ncRNAs …

Retracted: CRNDE promotes malignant progression of glioma by attenuating miR-384/PIWIL4/STAT3 Axis

J Zheng, X Liu, P Wang, Y Xue, J Ma, C Qu, Y Liu - Molecular therapy, 2016 - cell.com
Colorectal neoplasia differentially expressed (CRNDE) is the most upregulated long
noncoding RNA (lncRNA) in glioma. Herein, the function and potential molecular …

LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis

Y Tang, Y He, P Zhang, J Wang, C Fan, L Yang… - Molecular cancer, 2018 - Springer
Some of the key steps in cancer metastasis are the migration and invasion of tumor cells;
these processes require rearrangement of the cytoskeleton. Actin filaments, microtubules …