Association between APOA5 polymorphisms and susceptibility to metabolic syndrome: a systematic review and meta-analysis

S Mozafari, M Ashoori, SM Emami Meybodi, R Solhi… - BMC genomics, 2024 - Springer
Abstract Background The association between Apolipoprotein A5 (APOA5) genetic
polymorphisms and susceptibility to metabolic syndrome (MetS) has been established by …

Cohort profile update: Tehran cardiometabolic genetic study

MS Daneshpour, M Akbarzadeh, H Lanjanian… - European Journal of …, 2023 - Springer
The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study
that conducts periodic follow-ups. TCGS has created a comprehensive database comprising …

A genome-wide association study of metabolic syndrome in the Taiwanese population

CY Ho, JI Lee, SP Huang, SC Chen, JH Geng - Nutrients, 2023 - mdpi.com
The purpose of this study was to investigate genetic factors associated with metabolic
syndrome (MetS) by conducting a large-scale genome-wide association study (GWAS) in …

APOA1/C3/A4/A5 Gene Cluster at 11q23.3 and Lipid Metabolism Disorders: From Epigenetic Mechanisms to Clinical Practices

Q Xiao, J Wang, L Wang, H Ding - Biomedicines, 2024 - mdpi.com
The APOA1/C3/A4/A5 cluster is an essential component in regulating lipoprotein
metabolism and maintaining plasma lipid homeostasis. A genome-wide association analysis …

Genetic variations in IKZF3, LET7‐a2, and CDKN2B‐AS1: Exploring associations with metabolic syndrome susceptibility and clinical manifestations

A Paniri, MM Hosseini, S Fattahi… - Journal of Clinical …, 2024 - Wiley Online Library
Background and aim Metabolic syndrome (MetS) increases the risk of atherosclerosis and
diabetes, but there are no approved predictive markers. This study assessed the role of …

Disease patterns of coronary heart disease and type 2 diabetes harbored distinct and shared genetic architecture

H Xiao, Y Ma, Z Zhou, X Li, K Ding, Y Wu, T Wu… - Cardiovascular …, 2022 - Springer
Background Coronary heart disease (CHD) and type 2 diabetes (T2D) are two complex
diseases with complex interrelationships. However, the genetic architecture of the two …

Consumption of dietary fiber and APOA5 genetic variants in metabolic syndrome: baseline data from the Korean Medicine Daejeon Citizen Cohort Study

J Kim, Y Baek, S Lee - Nutrition & Metabolism, 2024 - Springer
Background Consumption of dietary fiber has been suggested as an important aspect of a
healthy diet to reduce the risk of metabolic syndrome (MetS), including cardiovascular …

Insulin resistance-related circulating predictive markers in the metabolic syndrome: a systematic review in the Iranian population

AS Zahedi, M Zarkesh, B Sedaghati-Khayat… - Journal of Diabetes & …, 2024 - Springer
Background Specific biomarkers for metabolic syndrome (MetS) may improve diagnostic
specificity for clinical information. One of the main pathophysiological mechanisms of MetS …

[HTML][HTML] Regularized machine learning models for prediction of metabolic syndrome using GCKR, APOA5, and BUD13 gene variants: Tehran cardiometabolic genetic …

N Alipour, A Kazemnejad, M Akbarzadeh… - Cell Journal …, 2023 - ncbi.nlm.nih.gov
Objective: Metabolic syndrome (MetS) is a complex multifactorial disorder that considerably
burdens healthcare systems. We aim to classify MetS using regularized machine learning …

[HTML][HTML] Nomogram developed with APOA5 genetic variant rs662799 and clinical characteristics predicting risk of essential hypertension in a Chinese population

D Abulaiti, S Abudureyimu, H Li, Y Cao… - … diagnosis and therapy, 2024 - ncbi.nlm.nih.gov
Background The apolipoprotein A5 (APOA5) gene has been identified as a key regulatory
factor in triglyceride (TG) metabolism and plasma lipid levels. Genetic polymorphisms of …