Interleukin-6 (IL-6) is a pleiotropic cytokine with roles in immunity, tissue regeneration, and
metabolism. Rapid production of IL-6 contributes to host defense during infection and tissue …

Disclosures: Dr. Narazaki reported grants from JSPS KAKENHI and grants from Chugai
Pharmaceutical Co., Ltd. during the conduct of the study; personal fees from Mitsubishi …

Since the outbreak of COVID-19 many studies have been published showing possible
therapies, here the author discusses the end of stage disease related drugs, like …

The ongoing outbreak of Coronavirus disease 2019 infection achieved pandemic status on
March 11, 2020. As of September 8, 2020 it has caused over 890,000 mortalities world-wide …

Rationale: Macrophages play critical roles in the pathogenesis of type 1 diabetes mellitus
(T1DM). Circular RNAs (circRNAs) are a novel class of endogenous RNAs with covalently …

Sepsis is a systemic inflammatory condition caused by an unbalanced immunological
response to infection, which affects numerous organs, including the intestines …

Objective To investigate the anti-cancer effect of Polygonatum sibiricum polysaccharides
(PSP) and the underlying mechanism. Methods Tumor-bearing mice were randomly divided …

Background: Increased IL-6 level, M2 macrophages and PD-1+ CD8+ T cells in tumor
microenvironments (TME) have been identified to correlate with resistance to checkpoint …

Pneumonia is an inflammatory disease that occurs in the lungs associated with pathogens
or other factors. It has been well established that long noncoding RNA X inactivate‐specific …

Background Myocardial infarction (MI) is a lethal manifestation of cardiovascular diseases.
Oxidative stress, inflammation, and subsequent cell death are known to play crucial roles in …