Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent form of chronic liver disease
that poses challenges in diagnosis and risk stratification. Non-alcoholic steatohepatitis …

Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Liver fibrosis should be assessed in all individuals with chronic liver disease as it predicts
the risk of future liver-related morbidity and thus need for treatment, monitoring and …

Chronic liver diseases (CLD) stem from various causes and lead to a gradual progression
that ultimately may result in fibrosis and eventually cirrhosis. This process is typically …

Cholestasis is a major pathological manifestation, often resulting in detrimental liver
conditions, which occurs in a variety of indications collectively termed cholestatic liver …

Introduction Accurate and reliable diagnosis and monitoring of hepatic fibrosis is
increasingly important given the variable natural history in chronic liver disease (CLD) and …

Background: SERPINA4/kallistatin is a multifunctional protein expressed from the liver; its
concentration in blood circulation reflects the degree of liver dysfunction and may serve as a …

Liver fibrosis is a pathological process in which excessive deposition of connective tissue
occurs in the liver. It is a response to chronic liver damage caused by viral agents, alcohol …

Extracellular vesicles (EVs), lipid bilayer-encapsulated membrane particles carrying
proteins, lipids, nucleic acids, and sugars, are shed by most cells into the extracellular milieu …

Cirrhosis of liver is an end stage of chronic liver insults from varied etiologies which leads to
impaired liver functions. Proteins expressed from liver and enters into circulation reflects …