Polymyxin and lipopeptide antibiotics: membrane-targeting drugs of last resort

EVK Ledger, A Sabnis, AM Edwards - Microbiology, 2022 - microbiologyresearch.org
The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …

[HTML][HTML] Molecular phenotyping approaches for the detection and monitoring of carbapenem-resistant Enterobacteriaceae by mass spectrometry

B Dixon, WM Ahmed, T Felton, SJ Fowler - … and Advances in the Clinical lab, 2022 - Elsevier
Antimicrobial resistance is increasing in prevalence and there is a clear need for the
development of rapid detection methods in clinical diagnostics. This review explores–omics …

Proteome profiling of evolved methicillin-resistant Staphylococcus aureus strains with distinct daptomycin tolerance and resistance phenotypes

JE Sulaiman, L Long, PY Qian, H Lam - Frontiers in Microbiology, 2022 - frontiersin.org
Methicillin-resistant Staphylococcus aureus (MRSA) is a highly dangerous pathogen, and
daptomycin has been increasingly used to treat its infections in clinics. Recently, several …

Elucidating the Mechanisms and Biological Consequences of Exogenous Fatty Acid Utilization by Staphylococcus aureus

EL Pruitt - 2024 - search.proquest.com
Staphylococcus aureus is a significant human pathogen known for its ability to cause a
range of infections, from minor skin conditions to life-threatening diseases. The ability of S …

Elucidation of the Role of VraTSR and Lipid Metabolism in the Development of Resistance Phenotypes in Staphylococcus aureus

T Shen - 2024 - search.proquest.com
Staphylococcus aureus is a gram-positive bacterium, which has developed resistance to
many antimicrobials. Methicillin-resistant S. aureus (MRSA) was first isolated in 1961. Since …

[图书][B] β-Lactam-Mediated Enhancement of Daptomycin Antibacterial Activity in Methicillin-Resistant Staphylococcus aureus

CI Lew - 2022 - search.proquest.com
Methicillin-resistant Staphylococcus aureus (MRSA) is a serious clinical threat due to innate
virulence properties, high infection rates, and the ability to develop resistance to multiple …

High Spatial Resolution Multi-Omic Investigations of Staphylococcus aureus Biofilm Layers: Visualizing Daptomycin-Resistance

ES Rivera - 2022 - search.proquest.com
Staphylococcus aureus infections pose a serious threat to human health with the increasing
incidence of microbial resistance to last-line antibiotics such as daptomycin. Many S. aureus …

Proteomic Study of Antibiotic Tolerance and Resistance in Bacterial Populations From Adaptive Laboratory Evolution

JE Sulaiman - 2022 - search.proquest.com
It is known that bacterial populations could quickly adapt to antibiotic treatments by
becoming tolerant and resistant to the drug. Recently, adaptive laboratory evolution (ALE) …