Estrogens are considered to play a major role in promoting the proliferation of both the
normal and the neoplastic breast epithelium. Their role as breast carcinogens has long been …

Reactive oxygen species (ROS) are increasingly recognized as critical determinants of
cellular signaling and a strict balance of ROS levels must be maintained to ensure proper …

MicroRNAs (miRNAs) are endogenous noncoding RNAs, which negatively regulate gene
expression. To determine genomewide miRNA DNA copy number abnormalities in cancer …

Introduction Adjuvant breast cancer therapy significantly improves survival, but
overtreatment and undertreatment are major problems. Breast cancer expression profiling …

Abstract Since Judah Folkman hypothesized in 1971 that angiogenesis is required for solid
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …

We have shown that smoking impacts bronchial airway gene expression and that
heterogeneity in this response associates with smoking-related disease risk. In this study …

Human papillomaviruses (HPVs) are involved in the pathogenesis of cancer of the cervix
(CaCx). MicroRNA (miRNA) expression analysis using Ambion (Austin, TX, USA) arrays …

Lung cancer is still the leading cause of cancer death worldwide. Both histologically and
molecularly lung cancer is heterogeneous. This review summarizes the current knowledge …

SLIT2 is a secreted polypeptide that guides migration of cells expressing Roundabout 1 and
2 (ROBO1 and ROBO2) receptors. Herein, we investigated SLIT2/ROBO signaling effects in …

Over the past few years, several genes, proteins and signalling pathways that are required
for embryogenesis have been shown to regulate tumour development and progression by …