Designing artificial microtissues by reaggregation of monodispersed primary cells,
neoplastic or engineered cell lines is providing insight into cell–cell interactions and …

Currently, researchers are using neural stem cell transplantation to promote regeneration
after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve …

The capacity of embryonic stem (ES) cells to form functional motoneurons (MNs) and
appropriate connections with muscle was investigated in vitro. ES cells were obtained from a …

Prolonged muscle denervation resulting from motor neuron (MN) damage leads to atrophy
and degeneration of neuromuscular junctions (NMJs), which can impart irreversible …

The neuromuscular junction (NMJ) is a unique, specialized chemical synapse that plays a
crucial role in transmitting and amplifying information from spinal motor neurons to skeletal …

OBJECTIVE The purpose of this review is to summarize the basic science literature related
to chronic nerve injuries, and to then use this as the background to provide emerging …

In Alzheimer's disease (AD), extensive neuronal loss and a deficiency of the
neurotransmitter acetylcholine (ACh) are the major characteristics during pathogenesis in …

BACKGROUND: Peripheral nerve damage mainly resulted from traumatic or infectious
causes; the main signs of a damaged nerve are the loss of sensory and/or motor functions …

Peripheral nerve regeneration is a complex process, with Wallerian degeneration the most
elementary reaction and Schwann cells playing an important role. In recent years, stem cells …

Although embryonic stem cells (ESCs) have enormous potentials due to their pluripotency,
their therapeutic use is limited by ethical, biological and safety issues. Compared to ESCs …