Postmitotic neurons require persistently active controls to maintain terminal differentiation.
Unlike dividing cells, aberrant cell cycle activation in mature neurons causes apoptosis …

Alzheimer's disease (AD) is the leading neurodegenerative pathology in aged individuals,
but many questions remain on its pathogenesis, and a cure is still not available. Recent …

Actin, a ubiquitous and highly conserved cytoskeletal protein, plays a pivotal role in various
cellular functions such as structural support, facilitating cell motility, and contributing to the …

A paradigm shift is currently taking place in the etiopathogenesis of neuropsychiatric
disorders as immunometabolism is replacing the earlier neurotransmitter model. According …

Tau is a microtubule-associated protein often found in neurofibrillary tangles (NFTs) in the
brains of patients with Alzheimer's disease. Beyond this context, mounting evidence …

Background Alzheimer's disease (AD) affects approximately 50 million people globally and
is expected to triple by 2050. Arctiin is a lignan found in the Arctium lappa L. plant. Arctiin …

Objective This study aims to investigate may moesin deficiency resulted in
neurodevelopmental abnormalities caused by negative impact on synaptic signaling …

Reprogramming of adult somatic cells into induced pluripotent stem cells (iPSCs) resets the
aging clock. However, primed iPSCs can retain cell-of-origin epigenomic marks, especially …