Mammalian pseudokinase TRIB3 in normal physiology and disease: charting the progress in old and new avenues

T Ord, T Ord - Current Protein and Peptide Science, 2017 - ingentaconnect.com
Tribbles homolog 3 (TRIB3) is a mammalian gene that is upregulated in response to several
types of cell death-inducing cellular stress. The TRIB3 protein is a pseudokinase, a protein …

Liraglutide ameliorates palmitate-induced insulin resistance through inhibiting the IRS-1 serine phosphorylation in mouse skeletal muscle cells

Z Li, Y Zhu, C Li, Y Tang, Z Jiang, M Yang… - Journal of …, 2018 - Springer
Objective A reduction in insulin-stimulated glucose uptake in skeletal muscles is a
characteristic of insulin resistance and type 2 diabetes mellitus (T2DM). The glucagon-like …

Activating transcription factor 3 regulates chemokine expression in contracting C2C12 myotubes and in mouse skeletal muscle after eccentric exercise

R Fernández-Verdejo, AM Vanwynsberghe… - Biochemical and …, 2017 - Elsevier
Activating transcription factor (ATF) 3 regulates chemokine expression in various cell types
and tissues. Herein, we studied this regulation in contracting muscle cells in vitro, and in …

[HTML][HTML] TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme CHAC1

D Örd, T Örd, T Biene, T Örd - … et Biophysica Acta (BBA)-Molecular Cell …, 2016 - Elsevier
Arsenic, a metalloid with cytotoxic and carcinogenic effects related to the disruption of
glutathione homeostasis, induces the expression of ATF4, a central transcription factor in the …

[HTML][HTML] Atorvastatin alleviates cardiomyocyte apoptosis by suppressing TRB3 induced by acute myocardial infarction and hypoxia

WP Cheng, HM Lo, BW Wang, SK Chua, MJ Lu… - Journal of the Formosan …, 2017 - Elsevier
Background/Purpose TRB3 (tribbles 3), an apoptosis-regulated gene, increases during
endoplasmic reticulum stress. Hypoxia can induce inflammatory mediators and apoptosis in …

The reversal effect of physical exercise on aging-related increases in APPL2 content in skeletal muscle

PH Canciglieri, GK Kuga, VR Muñoz, RC Gaspar… - Life sciences, 2018 - Elsevier
Aims The aim of this study was to evaluate the effects of aging on intracellular adiponectin
signaling and the possible therapeutic effect of physical exercise. Main methods Fischer 344 …

An investigation on the antioxidant activity of Azoramide, a promising new anti-diabetic, on palmitate-induced insulin resistance in H9c2 cells.

EN OKATAN - Journal of Cellular Neuroscience & Oxidative …, 2018 - search.ebscohost.com
Azoramide is synthesized as a regulator of endoplasmic reticulum protein folding and
chaperon activity. Fu et. al (2015) showed that azoramide treatment leads to recovery of …

Effect of methylprednisolone and heparin, used in experimental unilateral testicular ischemiareperfusion injury, on oxidative stress in the kidney, liver and contralateral …

C MERTOĞLU - … of Cellular Neuroscience & Oxidative Stress, 2018 - search.ebscohost.com
The aim of this study was to investigate the effects of methylprednisolone (MP) and heparin
administration on oxidative stress in the different tissues. Twenty-four male Sprague-Dawley …