Multimaterial 3D and 4D bioprinting of heterogenous constructs for tissue engineering

A Chen, W Wang, Z Mao, Y He, S Chen… - Advanced …, 2024 - Wiley Online Library
Additive manufacturing (AM), which is based on the principle of layer‐by‐layer shaping and
stacking of discrete materials, has shown significant benefits in the fabrication of …

Responsive biomaterials: optimizing control of cancer immunotherapy

L Xue, AS Thatte, D Mai, RM Haley, N Gong… - Nature Reviews …, 2024 - nature.com
Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …

3D Multispheroid Assembly Strategies towards Tissue Engineering and Disease Modeling

T Zhu, Y Hu, H Cui, H Cui - Advanced Healthcare Materials, 2024 - Wiley Online Library
Cell spheroids (esp. organoids) as 3D culture platforms are popular models for representing
cell–cell and cell–extracellular matrix (ECM) interactions, bridging the gap between 2D cell …

Ferro-catalysis bioelectronics: progress and prospects

X Tang, Y Liu, L Li, Y Song, Y Dai, Y Yang, G Yuan… - Nano Energy, 2024 - Elsevier
Harnessing the ferro-catalytic effect to accelerate physiological-chemical reactions to
enhance the therapeutic impact of diseases is termed “ferro-catalysis bioelectronics”. Ferro …

Recreating metabolic interactions of the tumour microenvironment

R Curvello, N Berndt, S Hauser, D Loessner - Trends in Endocrinology & …, 2024 - cell.com
Tumours are heterogeneous tissues containing diverse populations of cells and an
abundant extracellular matrix (ECM). This tumour microenvironment prompts cancer cells to …

[HTML][HTML] Programming temporal stiffness cues within extracellular matrix hydrogels for modelling cancer niches

G Major, M Ahn, WW Cho, M Santos, J Wise… - Materials Today Bio, 2024 - Elsevier
Extracellular matrix (ECM) stiffening is a common occurrence during the progression of
many diseases, such as breast cancer. To accurately mimic the pathophysiological context …

The importance of 3D fibre architecture in cancer and implications for biomaterial model design

JC Ashworth, TR Cox - Nature Reviews Cancer, 2024 - nature.com
The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …

Microbe-material hybrids for therapeutic applications

M Chen, L Xia, C Wu, Z Wang, L Ding, Y Xie… - Chemical Society …, 2024 - pubs.rsc.org
As natural living substances, microorganisms have emerged as useful resources in
medicine for creating microbe-material hybrids ranging from nano to macro dimensions. The …

Hydrogel‐Embedded Precision‐Cut Lung Slices Model Lung Cancer Premalignancy Ex Vivo

R Blomberg, K Sompel, C Hauer… - Advanced …, 2024 - Wiley Online Library
Lung cancer is the leading global cause of cancer‐related deaths. Although smoking
cessation is the best prevention, 50% of lung cancer diagnoses occur in people who have …

Biomimetic Tertiary Lymphoid Structures with Microporous Annealed Particle Scaffolds for Cancer Postoperative Therapy

G Kuang, Q Zhang, W Li, Y Zhao - ACS nano, 2024 - ACS Publications
Immunotherapy plays a vital role in cancer postoperative treatment. Strategies to increase
the variety of immune cells and their sustainable supply are essential to improve the …