Podosomes and invadopodia are actin-based dynamic protrusions of the plasma membrane
of metazoan cells that represent sites of attachment to—and degradation of—the …

After induction and specification in the ectoderm, at the border of the neural plate, the neural
crest (NC) population leaves its original territory through a delamination process. Soon …

The neural crest (NC) is a highly migratory multipotent cell population that forms at the
interface between the neuroepithelium and the prospective epidermis of a developing …

This review addresses the cellular and molecular mechanisms of cadherin-based tissue
morphogenesis. Tissue physiology is profoundly influenced by the distinctive organizations …

Proteolytic enzymes belonging to the A Disintegin And Metalloproteinase (ADAM) family are
able to cleave transmembrane proteins close to the cell surface, in a process referred to as …

Immunity, embryogenesis and tissue repair rely heavily on cell migration. Cells can be seen
migrating as individuals or large groups. In the latter case, collectiveness emerges via cell …

Directional cell migration is required for proper embryogenesis, immunity, and healing, and
its underpinning regulatory mechanisms are often hijacked during diseases such as chronic …

The neural crest serve as an excellent model to better understand mechanisms of embryonic
cell migration. Cell tracing studies have shown that cranial neural crest cells (CNCCs) …

Cadherin receptors have a well-established role in cell–cell adhesion, cell polarization and
differentiation. However, some cadherins also promote cell and tissue movement during …

Neural crest cells (NCCs) are a dynamic, multipotent, vertebrate-specific population of
embryonic stem cells. These ectodermally-derived cells contribute to diverse tissue types in …