A comprehensive study on the synthesis of 5-fluoroalkyl-substituted isoxazoles starting from
functionalized halogenoximes is reported. One-pot metal-free [3+ 2] cycloaddition of CF3 …

The cycloaddition reaction of N-hydroxysuccinimide ester and isocyanatoacetate catalyzed
by copper was described. A series of 4, 5-disubstituted oxazole compounds, including ones …

Optimized protocols for the synthesis of diazolyl α, α-difluoroacetates via deoxofluorination
of the corresponding glyoxylates with Morph-DAST are described. The method allowed the …

A series of new 2-aryl 5-sulfonyl-1, 3-oxazole-4-carboxylates for NCI anticancer screening
protocol against 60 cancer cell lines were synthesized. Screening was performed in vitro on …

An efficient approach to the preparation of β‐alkoxyenones bearing (het) aryl difluoromethyl
substituents is described. The method included acylation of acyclic or cyclic vinyl ethers with …

ABSTRACT A two-step approach to the synthesis of ω-CF 3 O-substituted aliphatic sulfonyl
chlorides is reported. The method is based on the reaction of alkylating agents bearing a ω …

Base‐promoted cyclization of N‐Boc‐ω‐(4‐(chloromethyl) oxazol‐5‐yl) alkylamines led to
the corresponding “dimerization” products containing fused 10‐, 12‐, and 14‐membered …

An efficient approach to the preparation of N-substituted 2-(pyrazol-4-yl) ethanols based on
recyclization reaction of 3-(dimethoxymethyl)-2-methoxytetrahydrofuran with hydrazines is …