Prefrontal cortex, amygdala, and threat processing: implications for PTSD

M Alexandra Kredlow, RJ Fenster, ES Laurent… - …, 2022 - nature.com
Posttraumatic stress disorder can be viewed as a disorder of fear dysregulation. An
abundance of research suggests that the prefrontal cortex is central to fear processing—that …

Recent advances in studying brain‐behavior interactions using functional imaging: The primary startle response pathway and its affective modulation in humans

J Wendt, M Kuhn, AO Hamm, TB Lonsdorf - Psychophysiology, 2023 - Wiley Online Library
The startle response is a cross‐species defensive reflex that is considered a key tool for
cross‐species translational emotion research. While the neural pathway mediating …

Fear extinction retention: is it what we think it is?

TB Lonsdorf, CJ Merz, MA Fullana - Biological Psychiatry, 2019 - Elsevier
There has been an explosion of research on fear extinction in humans in the past 2
decades. This has not only generated major insights, but also brought a new goal into focus …

l-DOPA and consolidation of fear extinction learning among women with posttraumatic stress disorder

JM Cisler, AA Privratsky, A Sartin-Tarm… - Translational …, 2020 - nature.com
This study tested whether l-DOPA delivered during the consolidation window following fear
extinction learning reduces subsequent fear responding among women with PTSD. Adult …

Aerobic exercise and consolidation of fear extinction learning among women with posttraumatic stress disorder

KM Crombie, A Sartin-Tarm, K Sellnow… - … Research and Therapy, 2021 - Elsevier
This study tested whether aerobic exercise delivered during the consolidation window
following fear extinction learning reduces the return of fear among women with posttraumatic …

Aerobic exercise after extinction learning reduces return of fear and enhances memory of items encoded during extinction learning

KM Crombie, A Azar, C Botsford, M Heilicher… - Mental health and …, 2023 - Elsevier
Fear conditioning paradigms are widely used in laboratory settings to discover treatments
that enhance memory consolidation and various fear processes (extinction learning, limit …

Sometimes I feel the fear of uncertainty: How intolerance of uncertainty and trait anxiety impact fear acquisition, extinction and the return of fear

A Wroblewski, M Hollandt, Y Yang… - International Journal of …, 2022 - Elsevier
It is hypothesized that the ability to discriminate between threat and safety is impaired in
individuals with high dispositional negativity, resulting in maladaptive behavior. A large body …

Contextual reinstatement promotes extinction generalization in healthy adults but not PTSD

AC Hennings, M McClay, JA Lewis-Peacock… - Neuropsychologia, 2020 - Elsevier
For episodic memories, reinstating the mental context of a past experience improves
retrieval of memories formed during that experience. Does context reinstatement serve a …

Fear in the mind's eye: The neural correlates of differential fear acquisition to imagined conditioned stimuli

L Burleigh, SG Greening - Social Cognitive and Affective …, 2023 - academic.oup.com
Mental imagery is involved in both the expression and treatment of fear-related disorders
such as anxiety and post-traumatic stress disorder. However, the neural correlates …

Quantification choices for individual differences: An example of mapping self-report to psychophysiological responses

J Morriss, N Biagi, S Wake - International Journal of Psychophysiology, 2024 - Elsevier
A popular focus in affective neuroscience research has been to map the relationships
between individual differences (eg personality and environmental experiences) and …