Bone marrow mesenchymal stem/stromal cells (BMSCs), which are known as multipotent
cells, are widely used in the treatment of various diseases via their self-renewable …

The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …

Background In the bone marrow, MSCs reside in a hypoxic milieu (1–5% O 2) that is thought
to preserve their multipotent state. Typically, in vitro expansion of MSCs is performed under …

Purpose To compare the number and properties of bone marrow stromal cells (BMSCs)
collected from bone marrow aspirate concentrate (BMAC) obtained from different harvest …

Purpose The purpose of this double-blind randomized controlled trial (RCT) was to compare
clinical improvement and radiographic findings up to 2 years of follow-up of a single intra …

Mesenchymal stromal cells (MSC) have become a popular treatment modality in equine
orthopaedics. Regenerative therapies are especially interesting for pathologies like …

Acute liver failure (ALF) is a high-mortality syndrome for which liver transplantation is
considered the only effective treatment option. A shortage of donor organs, high costs and …

The field of orthopedic surgery has seen a rapid increase in the use of various biologic
agents for the treatment of common musculoskeletal injuries. Most biologic agents attempt to …

In an ever-aging society the demand for bone-defect filling grafts continues to gain in
importance. While autologous grafting still prevails as the gold standard, allografts and …

Harvesting of autografts results in donor site morbidities and is limited in scenarios such as
large total body surface area burns. In these instances, coverage is increased by meshing …