Light‐Driven Radiochemistry with Fluorine‐18, Carbon‐11 and Zirconium‐89

D Lin, LM Lechermann, MP Huestis… - Angewandte Chemie …, 2024 - Wiley Online Library
This review discusses recent advances in light‐driven radiochemistry for three key isotopes:
fluorine‐18, carbon‐11, and zirconium‐89, and their applications in positron emission …

Recent advances in photochemistry for positron emission tomography imaging

JJ Zhang, L Lou, R Lv, J Chen, Y Li, G Wu, L Cai… - Chinese Chemical …, 2024 - Elsevier
As a powerful noninvasive imaging technology, positron emission tomography (PET) has
been playing an important role in disease theranostics and drug discovery. The successful …

Fluorspar to fluorochemicals upon low-temperature activation in water

I Klose, C Patel, A Mondal, A Schwarz, G Pupo… - Nature, 2024 - nature.com
The dangerous chemical hydrogen fluoride sits at the apex of the fluorochemical industry,
but the substantial hazards linked to its production under harsh conditions (above 300 …

Room-temperature photochemical copper-mediated fluorination of aryl iodides

TE Spiller, K Donabauer, AF Brooks, JA Witek… - Organic …, 2024 - ACS Publications
This report describes a method for the photochemical Cu-mediated fluorination of aryl
iodides with AgF via putative aryl radical (Ar•) intermediates. It involves irradiating an aryl …

11C‐Cyanation of Aryl Fluorides via Nickel and Lithium Chloride‐Mediated C−F Bond Activation

Z Zhang, T Niwa, K Watanabe… - Angewandte Chemie, 2023 - Wiley Online Library
Aryl fluorides are expected to be useful as radiolabeling precursors due to their chemical
stability and ready availability. However, direct radiolabeling via carbon‐fluorine (C− F) …

Generation and Application of Aryl Radicals Under Photoinduced Conditions

A Das, KR Justin Thomas - Chemistry–A European Journal, 2024 - Wiley Online Library
Photoinduced aryl radical generation is a powerful strategy in organic synthesis that
facilitates the formation of diverse carbon‐carbon and carbon‐heteroatom bonds. The …

Alkylthiolation of Aryl Halides under Electrochemical Conditions

Y Fan, T Zhang, M Wu, P Liu, P Sun - The Journal of Organic …, 2024 - ACS Publications
An electrochemical protocol for the alkylthiolation of aryl halides was developed. By using
dialkyl disulfides as the alkylthio sources, Mg plate as the sacrificial anode and graphite felt …

Palladium Catalyzed Cyanation of Diaryl Sulfoxides

X Qiu, G Qu, B Cui, C Cao, Y Shi - The Journal of Organic …, 2024 - ACS Publications
Aryl nitriles are highly versatile and useful compounds. A palladium-catalyzed cyanation of
diaryl sulfoxides using bench-stable Zn (CN) 2 as the cyanating reagent has been …

Photo- and Cu-Mediated 11C Cyanation of (Hetero)Aryl Thianthrenium Salts

K Cheng, EW Webb, GD Bowden, JS Wright… - Organic …, 2024 - ACS Publications
We present a photo-and Cu-mediated 11C cyanation of bench-stable (hetero) aryl
thianthrenium salts via an aryl radical addition pathway. The thianthrenium substrates can …

A chemoselective hydroxycarbonylation and 13 C-labeling of aryl diazonium salts using formic acid as the C-1 source

S Mondal, S Nandi, S Das, R Jana - Chemical Communications, 2024 - pubs.rsc.org
We report a one-pot synthesis of aryl carboxylic acids utilizing HCOOH as a CO surrogate
with low Pd-catalyst loading. This operationally simple and scalable method does not …