Rosmarinic acid and related dietary supplements: Potential applications in the prevention and treatment of cancer

J Zhao, L Xu, D Jin, Y Xin, L Tian, T Wang, D Zhao… - Biomolecules, 2022 - mdpi.com
Cancer constitutes a severe threat to human health and quality of life and is one of the most
significant causes of morbidity and mortality worldwide. Natural dietary products have drawn …

The role of MUC1 in renal cell carcinoma

M Milella, M Rutigliano, F Lasorsa, M Ferro, R Bianchi… - Biomolecules, 2024 - mdpi.com
Mucins are a family of high-molecular-weight glycoproteins. MUC1 is widely studied for its
role in distinct types of cancers. In many human epithelial malignancies, MUC1 is frequently …

[HTML][HTML] Front-line chemoimmunotherapy for treating epithelial ovarian cancer: Part II promising results of phase 2 study of paclitaxel-carboplatin-oregovomab regimen

ST Yang, WH Chang, FW Chou, HH Liu, WL Lee… - Taiwanese Journal of …, 2024 - Elsevier
In the Part I, we have discussed the background of CA125 and the development of anti-
CA125 monoclonal antibody (MAb) to highlight the potential role of CA125 and anti-CA125 …

CAR based immunotherapy of solid tumours—A clinically based review of target antigens

J Maher, DM Davies - Biology, 2023 - mdpi.com
Simple Summary Cancer accounts for an increasing number of deaths year on year.
However, new immune-based therapies offer promise in the quest to address this unmet …

MUC16 promotes triple-negative breast cancer lung metastasis by modulating RNA-binding protein ELAVL1/HUR

S Chaudhary, MI Appadurai, SK Maurya… - Breast Cancer …, 2023 - Springer
Background Triple-negative breast cancer (TNBC) is highly aggressive with an increased
metastatic incidence compared to other breast cancer subtypes. However, due to the …

[HTML][HTML] Identifying endoplasmic reticulum stress-related molecular subtypes and prognostic model for predicting the immune landscape and therapy response in …

B Zhang, X Chen, Z Wang, F Guo, X Zhang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Endoplasmic reticulum stress (ERS) is caused by the accumulation of intracellular misfolded
or unfolded proteins and is associated with cancer development. In this study, pan-cancer …

[HTML][HTML] Bromelain and acetylcysteine (BromAc®): A novel approach to the treatment of mucinous tumours

HK Wen, SJ Valle, DL Morris - American Journal of Cancer …, 2023 - ncbi.nlm.nih.gov
Mucins are a significant extracellular component of neoplastic entities such as
pseudomyxoma peritonei and several gastrointestinal adenocarcinomas. Mucinous tumours …

A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity

D Lee, H Ahn, HI Sim, E Choi, S Choi, Y Jo… - Journal of Experimental …, 2023 - Springer
Background Immunotherapy has significantly advanced cancer treatments, but many
patients do not respond to it, partly due to immunosuppressive mechanisms used by tumor …

Immunotherapy for triple negative breast cancer: the end of the beginning or the beginning of the end?

MZ Wojtukiewicz, M Pogorzelska… - Cancer and Metastasis …, 2022 - Springer
Triple-negative breast cancer (TNBC), which comprises 10–20% of all breast malignancies,
remains a subtype with the most dismal prognosis. TNBC cells, due to lack of estrogen (ER) …

Anti-glycan monoclonal antibodies: Basic research and clinical applications

KM Gillmann, JS Temme, S Marglous, CE Brown… - Current opinion in …, 2023 - Elsevier
Anti-glycan monoclonal antibodies have important applications in human health and basic
research. Therapeutic antibodies that recognize cancer-or pathogen-associated glycans …