M Milella, M Rutigliano, F Lasorsa, M Ferro, R Bianchi… - Biomolecules, 2024 - mdpi.com
Mucins are a family of high-molecular-weight glycoproteins. MUC1 is widely studied for its role in distinct types of cancers. In many human epithelial malignancies, MUC1 is frequently …
ST Yang, WH Chang, FW Chou, HH Liu, WL Lee… - Taiwanese Journal of …, 2024 - Elsevier
In the Part I, we have discussed the background of CA125 and the development of anti- CA125 monoclonal antibody (MAb) to highlight the potential role of CA125 and anti-CA125 …
Simple Summary Cancer accounts for an increasing number of deaths year on year. However, new immune-based therapies offer promise in the quest to address this unmet …
Background Triple-negative breast cancer (TNBC) is highly aggressive with an increased metastatic incidence compared to other breast cancer subtypes. However, due to the …
B Zhang, X Chen, Z Wang, F Guo, X Zhang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Endoplasmic reticulum stress (ERS) is caused by the accumulation of intracellular misfolded or unfolded proteins and is associated with cancer development. In this study, pan-cancer …
HK Wen, SJ Valle, DL Morris - American Journal of Cancer …, 2023 - ncbi.nlm.nih.gov
Mucins are a significant extracellular component of neoplastic entities such as pseudomyxoma peritonei and several gastrointestinal adenocarcinomas. Mucinous tumours …
D Lee, H Ahn, HI Sim, E Choi, S Choi, Y Jo… - Journal of Experimental …, 2023 - Springer
Background Immunotherapy has significantly advanced cancer treatments, but many patients do not respond to it, partly due to immunosuppressive mechanisms used by tumor …
MZ Wojtukiewicz, M Pogorzelska… - Cancer and Metastasis …, 2022 - Springer
Triple-negative breast cancer (TNBC), which comprises 10–20% of all breast malignancies, remains a subtype with the most dismal prognosis. TNBC cells, due to lack of estrogen (ER) …
KM Gillmann, JS Temme, S Marglous, CE Brown… - Current opinion in …, 2023 - Elsevier
Anti-glycan monoclonal antibodies have important applications in human health and basic research. Therapeutic antibodies that recognize cancer-or pathogen-associated glycans …