The effect of SSRIs on unconditioned anxiety: a systematic review and meta-analysis of animal studies

EJ Heesbeen, T van Kampen, PM Verdouw… - …, 2024 - Springer
Rationale Selective serotonin reuptake inhibitors (SSRIs) are the first choice of treatment for
anxiety-like disorders. However, which aspects of anxiety are affected by SSRIs is not yet …

Chemical compositions and pharmacological activities of natural musk (Moschus) and artificial musk: A review

S Lv, Z Lei, G Yan, SA Shah, S Ahmed, T Sun - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Natural musk (Moschus), derived naturally from
male musk deer (Moschus berezovskii Flerov, Moschus sifanicus Przewalski, or Moschus …

Muscone ameliorates LPS-induced depressive-like behaviors and inhibits neuroinflammation in prefrontal cortex of mice

MC He, Z Shi, M Qin, NN Sha, Y Li, DF Liao… - The American Journal …, 2020 - World Scientific
Depression is partially caused by inflammation in the central nervous system. Early study
demonstrated that musk, glandular secretion from male musk deer, exerted an …

Chronic hippocampal abnormalities and blunted HPA axis in an animal model of repeated unpredictable stress

M Algamal, JO Ojo, CP Lungmus, P Muza… - Frontiers in behavioral …, 2018 - frontiersin.org
Incidence of post-traumatic stress disorder (PTSD) ranges from 3 to 30% in individuals
exposed to traumatic events, with the highest prevalence in groups exposed to combat …

[HTML][HTML] Moschus exerted protective activity against H2O2-induced cell injury in PC12 cells through regulating Nrf-2/ARE signaling pathways

D Xie, T Deng, Z Zhai, T Qin, C Song, Y Xu… - Biomedicine & …, 2023 - Elsevier
The pivotal characteristics of Alzheimer's disease (AD) are irreversible memory loss and
progressive cognitive decline, eventually causing death from brain failure. In the various …

Zoology, chemical composition, pharmacology, quality control and future perspective of Musk (Moschus): a review

K Liu, L Xie, M Deng, X Zhang, J Luo, X Li - Chinese medicine, 2021 - Springer
Musk, the dried secretion from the musk sac gland which is located between the navel and
genitals of mature male musk deer, is utilized as oriental medicine in east Asia. It has been …

Ocimum basilicum (Basil) Modulates Apoptosis and Neurogenesis in Olfactory Pulp of Mice Exposed to Chronic Unpredictable Mild Stress

NN Ayuob, MJ Balgoon, S Ali, IS Alnoury… - Frontiers in …, 2020 - frontiersin.org
Background Ocimum basilicum (O. basilicum) was described to have antidepressant and
anxiolytic activities. Although the relationship between the main olfactory bulb (MOB) and …

Muscone can improve spinal cord injury by activating the angiogenin/plexin-B2 Axis

Y Zhou, S Guo, BOA Botchway, Y Zhang, T Jin… - Molecular …, 2022 - Springer
Spinal cord injury (SCI) is a devastating neurological disorder that usually damages
sensorimotor and autonomic functions. Signaling pathways can play a key role in the repair …

Water extract of moschus alleviates erastin-induced ferroptosis by regulating the Keap1/Nrf2 pathway in HT22 cells

C Song, Z Chu, J Dai, D Xie, T Qin, L Xie, Z Zhai… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Moschus, first described in the Shennong's Classic of the
Materia medicine, is a scarce and precious animal medicine. Modern pharmacological …

Comparing the effect of fluoxetine, escitalopram, and sertraline, on the level of BDNF and depression in preclinical and clinical studies: a systematic review

N Talaee, S Azadvar, S Khodadadi, N Abbasi… - European Journal of …, 2024 - Springer
Brain-derived neurotrophic factor (BDNF) dysfunction is one of the most important
mechanisms underlying depression. It seems that selective serotonin reuptake inhibitors …