Generation of 2′, 3′-cyclic phosphate-containing RNAs as a hidden layer of the transcriptome
M Shigematsu, T Kawamura, Y Kirino - Frontiers in genetics, 2018 - frontiersin.org
Cellular RNA molecules contain phosphate or hydroxyl ends. A 2′, 3′-cyclic phosphate
(cP) is one of the 3′-terminal forms of RNAs mainly generated from RNA cleavage by …
(cP) is one of the 3′-terminal forms of RNAs mainly generated from RNA cleavage by …
Discovery of the major 15–30 nt mammalian small RNAs, their biogenesis and function
H Lai, N Feng, Q Zhai - Nature Communications, 2023 - nature.com
Abstract Small RNAs (sRNAs) within 15-30 nt such as miRNA, tsRNA, srRNA with 3'-OH
have been identified. However, whether these sRNAs are the major 15-30 nt sRNAs is still …
have been identified. However, whether these sRNAs are the major 15-30 nt sRNAs is still …
RNA 3'-terminal phosphate cyclases and cyclase-like proteins
W Filipowicz - Postępy Biochemii, 2016 - postepybiochemii.ptbioch.edu.pl
RNA molecules bearing terminal 2', 3'-cyclic phosphate are quite common in nature. For
example, 2', 3'-cyclic phosphate termini are produced during RNA cleavage by many en …
example, 2', 3'-cyclic phosphate termini are produced during RNA cleavage by many en …
Site-specific acetylation of polynucleotide kinase 3′-phosphatase regulates its distinct role in DNA repair pathways
Abstract Mammalian polynucleotide kinase 3′-phosphatase (PNKP), a DNA end-
processing enzyme with 3′-phosphatase and 5′-kinase activities, is involved in multiple …
processing enzyme with 3′-phosphatase and 5′-kinase activities, is involved in multiple …
Chemical capping improves template switching and enhances sequencing of small RNAs
MG Wulf, S Maguire, N Dai, A Blondel… - Nucleic acids …, 2022 - academic.oup.com
Template-switching reverse transcription is widely used in RNA sequencing for low-input
and low-quality samples, including RNA from single cells or formalin-fixed paraffin …
and low-quality samples, including RNA from single cells or formalin-fixed paraffin …
A ribosomal RNA fragment with 2′, 3′-cyclic phosphate and GTP-binding activity acts as RIG-I ligand
S Jung, T von Thülen, I Yang, V Laukemper… - Nucleic acids …, 2020 - academic.oup.com
Abstract The RNA helicase RIG-I plays a key role in sensing pathogen-derived RNA. Double-
stranded RNA structures bearing 5′-tri-or diphosphates are commonly referred to as …
stranded RNA structures bearing 5′-tri-or diphosphates are commonly referred to as …
Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis
H Gu, S Yoshinari, R Ghosh… - Nucleic acids …, 2016 - academic.oup.com
An ATP-dependent RNA ligase from Methanobacterium thermoautotrophicum (MthRnl)
catalyzes intramolecular ligation of single-stranded RNA to form a closed circular RNA via …
catalyzes intramolecular ligation of single-stranded RNA to form a closed circular RNA via …
Synthesis of novel pyrophosphorothiolate-linked dinucleoside cap analogues in a ball mill
O Eguaogie, LA Cooke, PML Martin… - Organic & …, 2016 - pubs.rsc.org
Michaelis–Arbuzov reactions of S-aryl disulfide derivatives of 3′-thiothymidine or 5′-
thioadenosine with tris (trimethylsilyl) phosphite proceeded in high yields to the …
thioadenosine with tris (trimethylsilyl) phosphite proceeded in high yields to the …
Characterization of 3′-phosphate RNA ligase paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus highlights DNA and RNA 5′-phosphate capping activity …
WP Maughan, S Shuman - Journal of bacteriology, 2015 - Am Soc Microbiol
Escherichia coli RtcB exemplifies a family of GTP-dependent RNA repair/splicing enzymes
that join 3′-PO4 ends to 5′-OH ends via stable RtcB-(histidinyl-N)-GMP and transient …
that join 3′-PO4 ends to 5′-OH ends via stable RtcB-(histidinyl-N)-GMP and transient …
Genetic and Functional Analyses of Archaeal ATP-Dependent RNA Ligase in C/D Box sRNA Circularization and Ribosomal RNA Processing
Y Liu, Y Takagi, M Sugijanto, KDM Nguyen… - Frontiers in Molecular …, 2022 - frontiersin.org
RNA ligases play important roles in repairing and circularizing RNAs post-transcriptionally.
In this study, we generated an allelic knockout of ATP-dependent RNA ligase (Rnl) in the …
In this study, we generated an allelic knockout of ATP-dependent RNA ligase (Rnl) in the …